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Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

2016-10-11 01:02:31 | BioPortfolio

Published on BioPortfolio: 2016-10-11T01:02:31-0400

Clinical Trials [513 Associated Clinical Trials listed on BioPortfolio]

Agonist Replacement Therapy for Cocaine Dependence

Cocaine dependence is a significant public health concern. The proposed research will provide important clinical information regarding the efficacy of agonists replacement therapies for ma...

Free Treatment for Cocaine Dependence: A Placebo-Controlled Study of Mixed Amphetamine Salts (Adderall-XR) and Topiramate for the Treatment of Cocaine Dependence

The proposed protocol is a double-blind, placebo-controlled outpatient study of the safety and efficacy of Adderall-XR (ER-MAS) and topiramate in the treatment of cocaine dependence. Since...

Metabolic Effects of Cocaine

The goal of this this study is to elucidate the role of the HPA axis in the pathophysiology of cocaine dependence

Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study

The main purpose of this study is to determine if it is safe to use the study drug, clavulanic acid, in combination with cocaine. In this study, subjects will receive intravenous (i.v.) co...

Serotonin, Impulsivity, and Cocaine Dependence Treatment

The purpose of this study is to compare the effects of citalopram versus placebo given in the context of contingency management for cocaine dependence.

PubMed Articles [1657 Associated PubMed Articles listed on BioPortfolio]

How treatment improvement in ADHD and cocaine dependence are related to one another: A secondary analysis.

Attention-deficit hyperactivity disorder (ADHD) is overrepresented among individuals seeking treatment for substance use disorders. We previously reported that treatment with extended release mixed am...

Cognitive impairment associated with cocaine use: The role of co-existent alcohol abuse/dependence.

Cocaine abuse has been reported as leading to impaired cognitive function. However, cocaine abusers commonly also abuse alcohol, which can itself produce cognitive impairment. This study, therefore, a...

Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine.

Animal studies suggest that exposure to either of the two widely used drugs of abuse, heroin or cocaine, causes depletion of the antioxidant, reduced glutathione, a hallmark of oxidative stress, in th...

(-)-Stepholidine reduces cue-induced reinstatement of cocaine seeking and cocaine self-administration in rats.

Dopamine receptors are implicated in cocaine reward and seeking. We hypothesize that (-)-stepholidine, a dopamine D1/D2/D3 multi-receptor agent, would be effective in reducing cocaine reward and seeki...

Using a data science approach to predict cocaine use frequency from depressive symptoms.

Depressive symptoms may contribute to cocaine use. However, tests of the relationship between depression and severity of cocaine use have produced mixed results, possibly due to heterogeneity in indiv...

Medical and Biotech [MESH] Definitions

The purified, alkaloidal, extra-potent form of cocaine. It is smoked (free-based), injected intravenously, and orally ingested. Use of crack results in alterations in function of the cardiovascular system, the autonomic nervous system, the central nervous system, and the gastrointestinal system. The slang term "crack" was derived from the crackling sound made upon igniting of this form of cocaine for smoking.

SMOKING of COCAINE.

Disorders related or resulting from use of cocaine.

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Strong physiological and emotional dependence on OPIUM.

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