Effect of Photodynamic Therapy on Deep Caries in Permanent Tooth,A Controlled Clinical Trial

2016-10-12 01:38:21 | BioPortfolio


The aim of the proposed study is to assess the clinical effect of photodynamic therapy (PDT)using LED on dentin with carious lesions in permenent teeth. Patients with molars exhibiting deep carious lesions on the occlusal surface indicated for restorative treatment will be randomly allocated to two groups: Group 1 -Control after incomplete caries removel,indrect pulp treatment with calcium hydroxide(CH); Group 2 - PDT + CH after incomplete caries removel,disinfect the residual dentin with PDT(LED + methylene),then indrect pulp treatment with CH. Dentin samples will be removed before and after PDT for microbiological analysis. The microbiological samples will be cultured in Brucella blood agar, Mitis Salibarius-bacitracin agar and Rogosa SL agar. The teeth will then be restored using resin with clinical and radiographic follow up at six, 12 and 24 months. The data will be submitted to descriptive statistics.

Study Design

Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment


Dental Caries


Rubber dam isolation, Tooth drying, Dentin wash with sodium 0.9% saline, Antimicrobial Photodynamic Therapy


School and Hospital of Stomatology,Fujian Medical University




Fujian Medical University

Results (where available)

View Results


Published on BioPortfolio: 2016-10-12T01:38:21-0400

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