Therapeutic Conflicts and Multimorbidity

2016-10-12 01:38:21 | BioPortfolio


Clinical practice guidelines do not take into account multimorbidity and various potential therapeutic conflicts. Identifying and quantifying therapeutic conflicts is crucial in multimorbid patients having more than two acute or chronic diseases. Guidance should be available for frequent encountered situations, e.g. gastrointestinal bleeding or exacerbation of diabetes mellitus.


The study investigates multimorbidity in view of the occurrence of two different therapeutic conflicts or dilemma situations, respectively. The first concerns patients with diagnosis of gastrointestinal bleeding and prescription of anticoagulants or/and antiplatelet drugs (e.g., warfarin, clopidogrel and acetylsalicylic acid) as a risk factor for bleeding events. The second concerns patients with diagnosis of exacerbated diabetes mellitus and prescription of corticosteroids as a risk factor for worsening of blood glucose.

Study Design

Time Perspective: Retrospective


Gastrointestinal Hemorrhage


drug-drug or drug-disease interaction


University Hospital Zurich




University of Zurich

Results (where available)

View Results


Published on BioPortfolio: 2016-10-12T01:38:21-0400

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