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1. Observe and compare the chrono-chemotherapy IMRT and conventional chemotherapy and intensity modulated radiotherapy term efficacy of the treatment of locally advanced nasopharyngeal carcinoma.
2. Evaluation chrono-chemotherapy IMRT and conventional chemotherapy and intensity modulated radiotherapy in locally advanced nasopharyngeal carcinoma safety and tolerability.
3）observing the adverse reaction and effects of two groups,expected chrono-chemotherapy group can achieve lower toxicity, improve the curative effect, for the treatment of nasopharyngeal carcinoma provides a more reasonable way.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Esophageal Neoplasms [C06.405.117.430]
Chrono-chemotherapy pump:Melodie, Routine intravenous drip, induction Chrono-chemotherapy, induction Routine-chemotherapy, cisplatin chrono-chemotherapy, cisplatin routine-chemotherapy, intensity-modulated radiation therapy
Cancer Hospital of Guizhou Medical University
Guiyang Medical University
Published on BioPortfolio: 2016-10-19T02:38:21-0400
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Drug treatment designed to further diminish the disease toward complete remission following INDUCTION CHEMOTHERAPY. It helps to consolidate the gains during induction chemotherapy and may be followed by MAINTENANCE CHEMOTHERAPY.
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