Efficacy of Task-specific Training in Physical Activity Level Post-stroke

2016-10-19 02:38:21 | BioPortfolio


The majority of people after stroke demonstrate mobility limitations, which may reduce their physical activity levels. Task-specific training has shown to be an effective intervention to improve mobility in individuals with stroke, however, little is known about the impact of this intervention on levels of physical activity. The main objective will be to investigate the efficacy of a task-specific training, focused on both upper and lower limbs, in improving physical activity levels and mobility in individuals with stroke. The secondary objective will be to investigate the effect of the training, in improving muscle strength, exercise capacity, and quality of life. A randomized controlled trial with blinded assessment will assign eligible participants to either: 1) experimental group or 2) control group. Participants will receive interventions three times per week over 12 weeks. The experimental group will undertake task-specific training, while the control group will undertake global stretching and memory exercises, and health education sessions. Primary outcomes will include measures of physical activity levels and mobility, whereas secondary outcomes will be muscle strength, exercise capacity, and quality of life. The outcomes will be measured at baseline, 12 weeks post-intervention, and four and 12 weeks follow-up. The findings of this trial have the potential to provide important insights regarding the effects of task-specific training, focused on both upper and lower limbs, in preventing secondary post-stroke complications and improving the participants' general health through changes in physical activity levels.


The sample size was calculated considering the results of the Timed Up Go test reported by Yang et al., which involved a task-specific training program with individuals at the chronic phases of stroke. The Timed Up and Go test scores for the control and experimental groups at baseline were 14.3±7s and 14.6±7.4s, and after were 14.4±6.7s and 12.9±6.5s, respectively. Significant within and between-group differences were observed and the difference within the experimental group was -1.7±1.1s. Based upon this value, a sample size of 16 subjects per group, i.e. a total of 32 participants, would be required, considering a significance level (α) of 5% and a power of 0.80. Based on the assumption that about 15% of the participants may drop out during the course of the study, a target of 38 participants in total was set, 19 per group.

Data analyses will be performed by the SPSS for Windows® (release 17.0, SPSS Inc., Chicago, IL, USA). Descriptive statistics will be carried-out for all outcome variables. Differences between the groups at baseline will be investigated with the independent Student's t-tests for all variables related to the demographic and clinical characteristics. If differences between the groups at baseline exist, analysis of covariance will be used to eliminate the influence of extraneous factors.

The effects of the interventions will be analysed in two ways, namely from the data collected and by intention-to-treat analyses, where the last available value in the drop-outs will be carried forward to represent the missing data. Analyses of variance with repeated measures (2x4) will be employed to investigate the mean and interaction effects between the groups (intervention x control) and the time (pre-, post-interventions, and follow ups) for the primary physical activity level and mobility outcomes and the following secondary outcomes: muscular strength, exercise capacity, and SSQOL scores. Group descriptions will be presented as means and SD, and effect sizes at 95% confidence intervals will be reported.

The effect sizes will be calculated to determine the magnitude of the differences between the groups. The differences between the two mean values will be expressed in units of their SD, expressed as Cohen's d, or mean results for the experimental group minus the mean results for the control group, divided by the SD of the control group. Effect sizes between 0.2 and 0.5 will be considered small; between 0.5 and 0.8, medium; and above 0.8, large.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment




Task-specific training, Global stretching, memory exercises, health care orientation


Federal University of Minas Gerais
Belo Horizonte
Minas Gerais




Federal University of Minas Gerais

Results (where available)

View Results


Published on BioPortfolio: 2016-10-19T02:38:21-0400

Clinical Trials [2712 Associated Clinical Trials listed on BioPortfolio]

Dual Task in Institutionalized Elderly

Objectives: To evaluate the effects of eight weeks of cognitive motor training (dual task) in the risk of falls, balance, independence in basic activities of daily living (BADL) and handgr...

Effects of Self-Stretching Posture and Segmental Stabilization in Patients With Chronic Low Back Pain

Background: Low back pain is a major problem for public health that affects about 60-85% of the population at some point in life. Approximately 10-40% of individuals with low back pain dev...

Does Intensive Task Specific Training Improve Balance After Acute Stroke?

The aim of this study is to investigate whether additional task specific physiotherapy treatment and a self administrated home training program results in better balance compared to tradit...

Stretching and Strengthening Exercise in Fibromyalgia Patients

Fibromyalgia is a rheumatologic syndrome characterized by widespread chronic pain, tender points and other symptoms as fatigue, sleep disturbances, anxiety and depression. Therapeutic exer...

Bilateral Priming for Upper Extremity Hemiparesis in Older Adults

This study will compare bilateral priming followed by task specific training to health care education followed by the same task specific training protocol. The intention is to understand ...

PubMed Articles [29097 Associated PubMed Articles listed on BioPortfolio]

Bruxism: Is There an Indication for Muscle-Stretching Exercises?

Bruxism is a common phenomenon involving repetitive activation of the masticatory muscles. Muscle-stretching exercises are a recommended part of several international guidelines for musculoskeletal di...

Stretching Exercises Improve Vascular Endothelial Dysfunction Through Attenuation of Oxidative Stress in Chronic Heart Failure Patients With an Implantable Cardioverter Defibrillator.

Endurance training improves oxidative stress and vascular endothelial dysfunction in patients with chronic heart failure (CHF). However, patients with CHF and an implantable cardioverter defibrillator...

Acute effect of stretching modalities on global coordination and kicking accuracy in 12-13year-old soccer players.

The aim of the study was to compare the effect of stretching procedures on global coordination and accuracy in instep soccer kicks achieved in different stress conditions. Twenty male young soccer pla...

Immediate effects of different types of stretching exercises on badminton jump smash.

Since different types of stretching exercises may alter athletic performance, we compared the effects of three types of stretching exercises on badminton jump smash.

Augmentation of working memory training by transcranial direct current stimulation (tDCS).

Transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (dlPFC) can modulate working memory (WM) performance. However, evidence regarding the enhancement of WM training, i...

Medical and Biotech [MESH] Definitions

Exercises that stretch the muscle fibers with the aim to increase muscle-tendon FLEXIBILITY, improve RANGE OF MOTION or musculoskeletal function, and prevent injuries. There are various types of stretching techniques including active, passive (relaxed), static, dynamic (gentle), ballistic (forced), isometric, and others.

Education centers authorized by the Comprehensive Health Manpower Training Act, 1971, for the training of health personnel in areas where health needs are the greatest. May be used for centers other than those established by the United States act.

Technique based on muscle relaxation during self-hypnotic exercises. It is used in conjunction with psychotherapy.

A multi- and interdisciplinary field concerned with improving health and achieving equity in health for all people. It transcends national boundaries, promotes cooperation and collaboration within and beyond health science fields, and combines population-based disease prevention with individually-based patient care.

A nursing specialty created to answer the need for developing a global perspective in the practice of nursing in a world of interdependent nations and people. The focus of this nursing discipline is on the integration of international and transcultural content into the training. Courses include study in the area of cultural differences, nursing in other countries, and international health issues and organizations, as an example.

More From BioPortfolio on "Efficacy of Task-specific Training in Physical Activity Level Post-stroke"

Quick Search

Relevant Topics

Stroke - Cerebrovascular Disease (CVA)
A stroke is a serious medical condition that occurs when the blood supply to part of the brain is cut off. Strokes are a medical emergency and prompt treatment is essential because the sooner a person receives treatment for a stroke, the less damage is ...

Neurology - Central Nervous System (CNS)
Alzheimer's Disease Anesthesia Anxiety Disorders Autism Bipolar Disorders Dementia Epilepsy Multiple Sclerosis (MS) Neurology Pain Parkinson's Disease Sleep Disorders Neurology is the branch of me...

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Searches Linking to this Trial