Handgrip Strength Value in Predicting Mechanical Ventilation Weaning

2016-10-28 05:53:22 | BioPortfolio


The purpose of this study is to test the association between ICU acquired weakness as evaluated by dominant handheld dynamometry (handgrip) and the mechanical ventilation weaning outcome


Previous studies have evidenced that ICU acquired peripheral muscle weakness may lead to delayed mechanical ventilation weaning (i.e difficult or prolonged weaning according to guidelines). Nevertheless, no study has ever tested the association between handgrip strength and extubation outcome. We have generated the hypothesis that ICU acquired weakness, as tested by handgrip strength might be associated with extubation outcome. We have planned to include 240 patients. Handgrip strength will be monitored, along with a full muscular assessment through MRC score by the attending physiotherapist. Physicians in charge of the patients will be blinded to these values and the weaning protocol will continue according to guidelines.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care


Ventilator Weaning


Handheld dynamometry (handgrip strength)


Not yet recruiting


Assistance Publique - Hôpitaux de Paris

Results (where available)

View Results


Published on BioPortfolio: 2016-10-28T05:53:22-0400

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