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Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes

2016-11-01 07:23:21 | BioPortfolio

Summary

the investigators general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities from diverse settings.

Description

The specific aims of the proposed iHealth-T2D study are:

1. Determine whether intensive lifestyle modification vs usual care reduces risk of T2D (primary endpoint) amongst South Asians with i. central obesity; ii. prediabetes and iii. overall (with central obesity and / or obesity).

2. Investigate secondary endpoints, including health gains in family members. Identify social, demographic and environmental factors influencing primary and secondary endpoints.

3. Carry out a health economic analysis of lifestyle modifications vs usual care for prevention of T2D on the Indian subcontinent and Europe. Quantify the cost-effectiveness of screening by waist circumference vs HbA1c.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Type 2 Diabetes

Intervention

Intensive lifestyle modification

Location

Imperial College London
London
United Kingdom
W2 1PG

Status

Recruiting

Source

Imperial College London

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-11-01T07:23:21-0400

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