Track topics on Twitter Track topics that are important to you
There are no current alternatives to diagnostic contrast-requiring imaging for patients with an eGFR <30mL/min due to the association of gadolinium-based imaging modalities to nephrogenic systemic fibrosis and iodinated contrast-induced kidney injury. Ferumoxytol-enhanced imaging may offer an alternative approach.
1. Identify the resolution by which the coronary arteries can be visualized using ferumoxytol-enhanced cardiac magnetic resonance imaging in non-morbidly obese patients with prior regional cardiac ischemia localized by stress-induced echocardiography or technetium-based myocardial perfusion imaging.
2. Use ferumoxytol-enhanced cardiac MRI to quantify location and length of lesions in the left and right coronary arteries or in branching arteries that derive from the left or right coronary arteries.
3. Identify the resolution by which peripheral vasculature can be visualized using ferumoxytol-enhanced MR angiography and venography in patients with clinical findings consistent with peripheral vascular disease.
4. Use ferumoxytol-enhanced MR angiography and venography to quantify location and length of lesions in femoral arteries and branch vessels.
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Cardiology, Vascular Medicine
Brigham and Women's Hospital
Brigham and Women's Hospital
Published on BioPortfolio: 2016-11-04T08:38:21-0400
In this study the investigators would like to find out how a new iron containing Magnetic Resonance Imaging (MRI) contrast agent, called "ferumoxytol" can help the investigators to assess ...
This pilot early phase I trial studies how well ferumoxytol-enhanced magnetic resonance imaging (MRI) correlates with inflammatory (macrophage) responses in pediatric patients with maligna...
Current imaging techniques often do not demonstrate the true amount and location of brain tumors, which are both critical factors for treatment decision-making. This purpose of this study...
This study will define the effects of ferumoxytol on electrocardiogram (ECG) data as well as evaluate pharmacokinetics
Conventional vascular imaging techniques are often either contra-indicated in chronic kidney disease (CKD) patients due to their relative invasiveness, risks and cost. Computed tomography ...
Few data exist on internal medicine trainees' selection of cardiology training, although this is important for meeting future cardiology workforce needs.
Ferumoxytol is a superparamagnetic molecule originally developed as a contrast agent for magnetic resonance imaging. Elemental iron is contained within the carbohydrate core and is released slowly aft...
Noninvasively differentiating therapy-induced pseudo-progression from recurrent disease in patients with glioblastoma is prospectively difficult due to the current lack of a biologically specific imag...
To evaluate, if clinically translatable ferumoxytol nanoparticles can be used for in vivo detection and quantification of stem cell transplants with magnetic particle imaging (MPI).
The joint position paper of the working community "Cardiovascular Nuclear Medicine" of the German Society of Nuclear Medicine (DGN) and the working group "Nuclear Cardiology Diagnostics" of the German...
The study of the heart, its physiology, and its functions.
System of herbal medicine practiced in Japan by both herbalists and practitioners of modern medicine. Kampo originated in China and is based on Chinese herbal medicine (MEDICINE, CHINESE TRADITIONAL).
A modified Greco-Arabic medical system flourishing today as unani medicine. It was the product of Arab physicians and scholars captivated by Greek philosophy, science, and medicine. It is practiced today in India and Pakistan, largely as a type of herbal medicine. (From Magner, A History of Medicine, 1992, p136)
The hospital department responsible for the administration and provision of diagnostic and therapeutic services for the cardiac patient.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Chronic kidney disease (CKD), also known as chronic renal disease, is a progressive loss in renal function over a period of months or years. The symptoms of worsening kidney function are non-specific, and might include feeling generally unwell and experi...
Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dictionary of Medicine). It is becoming increasing common i...
Adhd Anorexia Depression Dyslexia Mental Health Psychiatry Schizophrenia Stress Mental health, although not being as obvious as physical health, is very important, causing great unhappiness to those affected, causing add...