The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions

2016-11-04 08:38:21 | BioPortfolio


The study will compare bacteria levels in cavities before and after silver diamine fluoride (SDF) treatment.


To assess the effect of silver diamine fluoride (SDF) treatment on microorganisms present in root caries or cervical lesions by collecting microbial deposits before and 1 month after SDF application. Bacterial samples will be collected from 20 adult subjects at the initial visit before application of SDF and one month after. At the 1 month recall, examination for caries arrest will be performed. All 40 bacterial samples will be sent to the Forsyth Institute to verify bacterial composition using HOMINGS technology.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment




Silver Diamine Fluoride (SDF)


University of Michigan School of Dentistry
Ann Arbor
United States


Not yet recruiting


University of Michigan

Results (where available)

View Results


Published on BioPortfolio: 2016-11-04T08:38:21-0400

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Medical and Biotech [MESH] Definitions

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Fluoride-releasing restorative materials made by the sintering of metal (usually silver) particles to glass ionomer powder. Glass ionomers are fluoride-releasing cements that are not very durable. Sintering of the metal particles is a means of improving those physical properties that will make the glass ionomer cement more durable.

The use of silver, usually silver nitrate, as a reagent for producing contrast or coloration in tissue specimens.

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Dentistry is the study, management and treatment of diseases and conditions affecting the mouth, jaw, teeth and their supporting tissues (Oxford Medical Dictionary) The work of a dentist ranges from regular patient check-up to orthodontics and surgery....

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