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" Effect of Affordance of Objects on the Memory: Study in Transcranial Magnetic Stimulation "

2016-11-08 09:23:22 | BioPortfolio

Summary

The purpose of this study is determine the involvement of motor system in the memory of manipulable objects. The idea is to stimulate the ventral premotor cortex with transcranial magnetic stimulation to see whether this stimulation will affect memory of manipulable objects.

Description

Embodied cognition claims that representations shares processing resources with sensorimotor systems. More specifically, it has been proposed that language comprehension relies on internal simulation of the meaning. For instance, numerous studies have shown that the processing of action-related concepts involve a motor activation similar to when the action is actually performed. However, even if those studies show clearly that action-related concepts involve a motor activation, such activations may be incidental to the activation of their representations, rather than part of it. Another way to show that this motor component takes part in the representation of manipulable objetcs is to investigate whether an impairment of motor system would impair the memory of manipulable object. In this study, investigators will use Transcranial Magnetic Stimulation (TMS) to stimulate ventral premotor cortex (PMv) to see whether this stimulation will affect memory of manipulable objects, but not memory of nonmanipulable objects. For this purpose, three TMS conditions will be assessed: cTBS to inhibit the motor cortex, iTBS to excite the motor cortex, and a SHAM condition as control.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Outcomes Assessor)

Conditions

Healthy

Intervention

PMv stimulation (iTBS), PMv inhibition (cTBS), Control (SHAM)

Location

Centre de Recherche Clinique (CRC) - CHSA
Paris
France
75014

Status

Not yet recruiting

Source

Centre Hospitalier St Anne

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-11-08T09:23:22-0500

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