Effect of Prebiotic Supplement on the Body Mass Index of Participants With Severe Obesity

2016-11-09 09:53:22 | BioPortfolio


Obese patients have a high level of intestinal microflora imbalance, with serious consequences such as loss of digestive function. Potential mediators of intestinal microbiota are prebiotics, supplements considered safe because they are naturally contained in food and human microbiota. Their use has been studied as new therapeutic approach for the regulation of intestinal microbiota in various situations of disease, including severe obesity.

This is a double-blind, placebo-controlled, randomized clinical trial to assess the effect of prebiotic supplementation (fructo-oligosaccharide - 12 g / day) on body mass index in participants with obesity class III, with follow up of 90 days.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Obesity Class III


Prebiotics, Placebo


Hospital Dona Helena
Santa Catarina


Not yet recruiting


Hospital Dona Helena

Results (where available)

View Results


Published on BioPortfolio: 2016-11-09T09:53:22-0500

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Obesity is the condition in which excess fat has accumulated in the body (mostly in subcutaneous tissues). clinical obesity is considered to be present when a person has a BMI of over 30 (Oxford Dictionary of Medicine). It is becoming increasing common i...

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