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Treatment of Metastatic Melanoma With TSA-CTL(Tumor Specific Antigen-Induced Cytotoxic T Lymphocytes)

2016-11-10 09:38:21 | BioPortfolio

Summary

The primary purpose of this study is to evaluate the safety of TSA-CTL in the treatment of the advanced melanoma.

The secondary purpose of this study is to evaluate preliminarily the effect of TSA-CTL in the treatment of the advanced melanoma.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Metastatic Melanoma

Intervention

TSA-CTL(Tumor Specific Antigen Induced Cytotoxic Lymphocyte), Cyclophosphamide, Cyclophosphamide, Fludarabine

Location

Sun Yat-Sen University Cancer Center
Guangzhou
Guangdong
China
510030

Status

Not yet recruiting

Source

BGI, China

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-11-10T09:38:21-0500

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Medical and Biotech [MESH] Definitions

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.

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Positional isomer of CYCLOPHOSPHAMIDE which is active as an alkylating agent and an immunosuppressive agent.

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