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Blood Glucose Response After Oral Intake of Lactulose in Healthy Volunteers

2016-11-21 13:17:11 | BioPortfolio

Summary

Prospective, open, mono-center, randomized, two part study with 4-way cross-over design in each study part.

The objective of the study is to investigate blood glucose levels after oral intake of defined amounts of lactulose.

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science

Conditions

Blood Glucose

Intervention

Lactulose crystals 10 g, Lactulose crystals 20 g, Lactulose liquid 10 g, Lactulose liquid 20 g, Oral glucose 20 g, Still water

Location

CRO BioTeSys GmbH
Esslingen
Germany
73728

Status

Not yet recruiting

Source

Fresenius Kabi

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-11-21T13:17:11-0500

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Medical and Biotech [MESH] Definitions

A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)

Materials in intermediate state between solid and liquid.

The transformation of a liquid to a glassy solid i.e., without the formation of crystals during the cooling process.

The removal of a soluble component from a liquid mixture by contact with a second liquid, immiscible with the carrier liquid, in which the component is preferentially soluble. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)

Miniaturized methods of liquid-liquid extraction.

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