The Effect of External Diaphragmatic Pacemaker on the Patients With Chronic Cor Pulmonale

2016-11-30 15:45:31 | BioPortfolio


This study evaluates the effect of external diaphragmatic pacemaker on the patients with chronic cor pulmonale. Half of participants will receive external diaphragmatic pacemaker, while the other half will receive routine therapy.


Investigate the effect of external diaphragmatic pacemaker on chronic cor pulmonale, the indicators include: respiratory muscle force, diaphragmatic degree of excursion and thickness, pulmonary artery pressure, respiratory distress, feeling of fatigue and quality of life, pulmonary function,NT-proBNP,PaO2 and PaCO2.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment


Chronic Cor Pulmonale


external diaphragmatic pacemaker group


Shanghai Tenth People's Hospital


Not yet recruiting


Tongji University

Results (where available)

View Results


Published on BioPortfolio: 2016-11-30T15:45:31-0500

Clinical Trials [754 Associated Clinical Trials listed on BioPortfolio]

Small Intestinal Absorption in Patients With Chronic Obstructive Pulmonary Disease and Cor Pulmonale

Aim: To investigate whether patients with pulmonary hypertension have reduced absorption capacity compared to COPD patients without cor pulmonale potentially due to venous obstruction in t...

Placement Of Cardiac PacemaKer Trial (POCKET)-RCT

Aim: To compare patient satisfaction with intramuscular placement of a pacemaker pocket to subcutaneous placement. Patients will be randomized (approximately half i each group) to receive...

Physical Activity and Pacemaker Study

The benefits of regular physical activity are well-established. Furthermore, our group has previously shown that in a population of patients with implanted pacemakers, those who exercise m...

ELR Monitoring Against Permanent Pacemaker in Atrial Fibrillation

Randomised crossover study comparing the sensitivity and specificity of 5 External loop recorders in detecting pacemaker detected Atrial fibrillation burden.

Diaphragmatic Echography in Critically Ill patientS

Acute respiratory failure (ARF) is characterised by a discrepancy between load imposed on respiratory muscles and their capacity. Recently, diaphragmatic ultrasonography has been introduce...

PubMed Articles [15532 Associated PubMed Articles listed on BioPortfolio]

Diaphragmatic eventration presenting as a recurrent diaphragmatic hernia.

Diaphragmatic eventration is an uncommon condition, usually discovered incidentally in asymptomatic patients. Even in symptomatic patients, the diagnosis can be challenging and should be considered am...

Mycobacterium Tuberculosis Infection at Pacemaker Implantation Site.

Expanding clinical indications of cardiac rhythm management have led to an increased use of pacemaker implantation which is associated with increased incidence of pacemaker infections. Staphylococcus ...

Cardiac resynchronization therapy outcomes in patients with chronic heart failure: cardiac resynchronization therapy with pacemaker versus cardiac resynchronization therapy with defibrillator.

Cardiac resynchronization therapy (CRT) for chronic heart failure with left ventricular systolic dysfunction (LVSD) consistently improves survival against optimal medical therapy alone. Limited data e...

Is mortality a useful parameter for public reporting in pacemaker implantation? Results of an obligatory external quality control programme.

To evaluate if public reporting of pacemaker implantation-associated mortality is meaningful in a large contemporary patient cohort.

Modeling pacemaker deterioration with age.

New JGP study models how sinoatrial node pacemaker activity changes in aged hearts.

Medical and Biotech [MESH] Definitions

A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).

The type of DIAPHRAGMATIC HERNIA caused by TRAUMA or injury, usually to the ABDOMEN.

A congenital abnormality characterized by the elevation of the DIAPHRAGM dome. It is the result of a thinned diaphragmatic muscle and injured PHRENIC NERVE, allowing the intra-abdominal viscera to push the diaphragm upward against the LUNG.

A bone fixation technique using an external fixator (FIXATORS, EXTERNAL) for lengthening limbs, correcting pseudarthroses and other deformities, and assisting the healing of otherwise hopeless traumatic or pathological fractures and infections, such as chronic osteomyelitis. The method was devised by the Russian orthopedic surgeon Gavriil Abramovich Ilizarov (1921-1992). (From Bull Hosp Jt Dis 1992 Summer;52(1):1)

The outer part of the hearing system of the body. It includes the shell-like EAR AURICLE which collects sound, and the EXTERNAL EAR CANAL, the TYMPANIC MEMBRANE, and the EXTERNAL EAR CARTILAGES.

More From BioPortfolio on "The Effect of External Diaphragmatic Pacemaker on the Patients With Chronic Cor Pulmonale"

Quick Search

Searches Linking to this Trial