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Comparasion Between NCRT and NCT Followed by MIE for Treatment of Locally Advanced Resectable ESCC

2016-12-26 23:17:36 | BioPortfolio

Summary

The purpose of this study is to evaluate the outcomes of neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy followed by minimally invasive esophagectomy on patients with locally advanced resectable esophageal squamous cell carcinoma(cT3-4N0-1M0).

Description

It is a prospective randomized phase III clinical trial sponsored by Shanghai Zhongshan Hospital with other eight hospitals in China participating in. 268 patients with locally advanced resectable esophageal squamous cell carcinoma(cT3-4aN0-1M0) are recruited and randomly assigned into the neoadjuvant chemoradiotherapy group (NCRT group) and the neoadjuvant chemotherapy group (NCT group) according to the proportion of 1:1.The safety,efficacy of protocals and prognosis of patients are compared between the two regmens.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Esophageal Squamous Cell Carcinoma Stage cT3-4N0-1M0

Intervention

Neoadjuvant Chemoradiotherapy, Neoadjuvant Chemotherapy

Location

Shanghai Zhongshan Hospital
Shanghai
Shanghai
China
200032

Status

Not yet recruiting

Source

Shanghai Zhongshan Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2016-12-26T23:17:36-0500

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