Castration-resistant Prostate Cancer and Intra-prostatic Hormonal Status

2017-01-10 03:53:21 | BioPortfolio


The main objective of the study is to determine the intra-prostatic concentration of sexual steroids when castration resistance appears in castration-resistant prostate cancer patients compared to patients naif of hormonal treatment

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label


Prostate Cancer


intra-prostatic concentration of sexual steroids, Trans-rectal biopsy


Hopital Foch


Not yet recruiting


Hopital Foch

Results (where available)

View Results


Published on BioPortfolio: 2017-01-10T03:53:21-0500

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Medical and Biotech [MESH] Definitions

A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

Conducting a biopsy procedure with the aid of a MEDICAL IMAGING modality.

A secreted prostate-specific protein which can bind non-polar steroids, cholesterol and a group of small, proline-rich peptides. The protein is specifically found in RATS and comprises three distinct secretoglobin-related subunits referred to as prostatic steroid-binding protein C1, C2 and C3.

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Relevant Topics

Prostate Cancer
Prostate cancer (cancer de prostata) Prostate cancer (cancer de prostata) is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostat...

Sexual Health
The World Health Organization (WHO) definition of sexual health; "the state of physical, emotional, mental and social well-being related to sexuality; it is not merely the absence of disease, dysfunction and infirmity. Sexual health requires a posit...

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