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Castration-resistant Prostate Cancer and Intra-prostatic Hormonal Status

2017-01-10 03:53:21 | BioPortfolio

Summary

The main objective of the study is to determine the intra-prostatic concentration of sexual steroids when castration resistance appears in castration-resistant prostate cancer patients compared to patients naif of hormonal treatment

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label

Conditions

Prostate Cancer

Intervention

intra-prostatic concentration of sexual steroids, Trans-rectal biopsy

Location

Hopital Foch
Suresnes
France
92150

Status

Not yet recruiting

Source

Hopital Foch

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-01-10T03:53:21-0500

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Medical and Biotech [MESH] Definitions

A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Tissue ablation of the PROSTATE performed by ultrasound from a transducer placed in the RECTUM. The procedure is used to treat prostate cancer (PROSTATIC NEOPLASMS) and benign prostatic hypertrophy (PROSTATIC HYPERPLASIA).

The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.

Conducting a biopsy procedure with the aid of a MEDICAL IMAGING modality.

A secreted prostate-specific protein which can bind non-polar steroids, cholesterol and a group of small, proline-rich peptides. The protein is specifically found in RATS and comprises three distinct secretoglobin-related subunits referred to as prostatic steroid-binding protein C1, C2 and C3.

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