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PD-L1 and Other Immuno-markers Influenced by Osimertinib Treatment in Advanced NSCLC Patients

2017-01-26 07:28:18 | BioPortfolio

Summary

The study will investigate whether PD-L1 and other immuno-markers will be influenced by osimertinib treatment in advanced epidermal growth factor receptor (EGFR)T790M positive advanced NSCLC patients. In addition, we will explore whether PD-L1 and other immuno-markers can predict the safety and efficacy of subsequent use of immune checkpoint inhibitors at the time of PD due to osimertinib resistance.

Description

Investigate whether PD-L1 and other immuno-markers will be influenced by osimertinib treatment in advanced EGFR T790M positive advanced NSCLC patients.

explore whether PD-L1 and other immuno-markers can predict the safety and efficacy of subsequent use of immune checkpoint inhibitors at the time of PD due to osimertinib resistance.

Study Design

Conditions

Small Cell Lung Cancer, Polygonal Type

Intervention

No interventions will be taken in this Observational study

Location

Fujian Medical University Union Hospital
Fuzhou
Fujian
China

Status

Not yet recruiting

Source

Guangdong Association of Clinical Trials

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-01-26T07:28:18-0500

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