Food Reward Processing in the Human Brain

2017-03-16 21:23:21 | BioPortfolio


The aim of this study is to investigate the influence of different metabolic states and hormonal satiety signalling on responses in neural reward networks.


Given the rapid development of obesity world-wide, a better understanding of the interaction between the encoding of food reward in mesocorticolimbic reward pathways and homeostatic energy regulation is of paramount importance for the development of new treatment strategies. Healthy participants will undergo functional magnetic resonance imaging while performing a task distinguishing between the anticipation and the receipt of either food or monetary reward. Every participant will be scanned twice in a counterbalanced fashion, both during a state of hunger (after 24-hours fasting) and satiety. Blood samples will be collected to assess hormonal satiety signalling. We hope to provide new insights into the neurobiological underpinnings of motivational processing and hedonic evaluation of food reward.

Study Design




Satiety State




University of Heidelberg Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2017-03-16T21:23:21-0400

Clinical Trials [425 Associated Clinical Trials listed on BioPortfolio]

Chewy Satiety - the Interplay Between Food Structure, Oral Processing and Satiety

This study examines if there are differences in satiety responses between structurally different wholegrain rye products.

Chronic Effects of Fats on Satiety & Energy Needs

The purpose of this study is to evaluate the effect of dietary fat on satiety (the experience of fullness between one meal and the next) and energy metabolism over an extended period of ti...

Assessment of Satiety Following Oral Administration of an Erythritol Sweetened Beverage

Erythritol is a low calorie sugar substitute that is being increasingly used to sweeten beverages and other food items. Greater amounts of erythritol are required to reach the sweetness le...

The Effect of Food Labelling and Satiety on Individuals Food Choice

Previous research has shown that nutritional knowledge is a key indicator in healthy eating choices, but real-life examinations of the associations between both nutritional knowledge and s...

Emulsion Droplet Physical State on Postprandial Lipemia and Satiety

The purpose of this study is to compare the changes in blood lipids and feelings of satiety after consumption of oil-in-water emulsions in which the droplets are in either the liquid or so...

PubMed Articles [10116 Associated PubMed Articles listed on BioPortfolio]

Consuming Lower-Protein Nutrition Bars with Added Leucine Elicits Postprandial Changes in Appetite Sensations in Healthy Women.

Higher-protein meals (>25 g protein/meal) have been associated with enhanced satiety but the role of amino acids is unclear. Leucine has been proposed to stimulate satiety in rodents but has not been ...

Influences of hunger, satiety and oral glucose on functional brain connectivity: A multimethod resting state fMRI study.

A major regulatory task of the organism is to keep brain functions relatively constant in spite of metabolic changes (e.g., hunger vs. satiety) or availability of energy (e.g., glucose administration)...

Satiety-induced enhanced neuronal activity in the frontal operculum relates to the desire for food in the obese female brain.

In the present pilot study, we questioned how eating to satiety affects cognitive influences on the desire for food and corresponding neuronal activity in the obese female brain. During EEG recording,...

High amylose cornstarch preloads stabilized postprandial blood glucose but failed to reduce satiety or food intake in healthy women.

High fiber diets promote satiety and sustain normal blood glucose by delaying digestion and slowing glucose absorption, but their longer-term impact on body weight loss is thought to be due primarily ...

Changes in Satiety Hormones in Response to Leptin Treatment in a Patient with Leptin Deficiency.

We tested whether leptin treatment affects secretion of satiety-related gut peptides and brain-derived neurotrophic factor (BDNF), which is a regulator of energy homeostasis downstream of hypothalamic...

Medical and Biotech [MESH] Definitions

Healthy People Programs are a set of health objectives to be used by governments, communities, professional organizations, and others to help develop programs to improve health. It builds on initiatives pursued over the past two decades beginning with the 1979 Surgeon General's Report, Healthy People, Healthy People 2000: National Health Promotion and Disease Prevention Objectives, and Healthy People 2010. These established national health objectives and served as the basis for the development of state and community plans. These are administered by the Office of Disease Prevention and Health Promotion (ODPHP). Similar programs are conducted by other national governments.

Behavioral response associated with the achieving of gratification.

Governmental guidelines and objectives pertaining to public food supply and nutrition including recommendations for healthy diet and changes in food habits to ensure healthy diet.

Behaviors associated with the ingesting of water and other liquids; includes rhythmic patterns of drinking (time intervals - onset and duration), frequency and satiety.

Surgical reinnervation of a denervated peripheral target using a healthy donor nerve and/or its proximal stump. The direct connection is usually made to a healthy postlesional distal portion of a non-functioning nerve or implanted directly into denervated muscle or insensitive skin. Nerve sprouts will grow from the transferred nerve into the denervated elements and establish contact between them and the neurons that formerly controlled another area.

More From BioPortfolio on "Food Reward Processing in the Human Brain"

Quick Search


Relevant Topics

Public Health
Alternative Medicine Cleft Palate Complementary & Alternative Medicine Congenital Diseases Dentistry Ear Nose & Throat Food Safety Geriatrics Healthcare Hearing Medical Devices MRSA Muscular Dyst...

Food is any substance consumed to provide nutritional support for the body. It is usually of plant or animal origin, and contains essential nutrients, such as carbohydrates, fats, proteins, vitamins, or minerals. The substance is ingested by an organism ...

Searches Linking to this Trial