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Viatorr CX Case-control Study for Complications of Portal Hypertension

2017-03-20 21:23:22 | BioPortfolio

Summary

To evaluate the clinical benefits in the patients receiving Viatorr CX over a period of 12 months of structured Follow-up (before TIPS, at TIPS, 1 week after TIPS, at 6 weeks, 4 months, 6 months, 9 months, 12 months), regarding clinical endpoints, such as HE, readmission, liver injury, cardiac function, response to TIPS and the passive expansion of the stents in real life.

Description

Case-control study using the patients in the University Clinic Bonn receiving Viatorr CX (n=40), using a comparison ration 1:1:1 to Viatorr and bare metal stents.

Of these patients, 20 patients will receive Viatorr CX and the assessement of the width of the stent as outlined in the JVIR-paper published this year.

The Viatorr and BMS controls with similar age, gender, Child, MELD and indication for TIPS.

A total of 125 patients with the primary composite-endpoint HE/readmission will be investigated Secondary endpoints are liver injury, cardiac function, response to TIPS and the passive expansion of the stents in real life.

Study Design

Conditions

Liver Cirrhoses

Intervention

TIPS

Location

Laboratory for Liver Fibrosis and Portal Hypertension
Bonn
Germany
53127

Status

Recruiting

Source

University Hospital, Bonn

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-03-20T21:23:22-0400

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Medical and Biotech [MESH] Definitions

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Molecule produced in plant leaves that acts like a hormone by inducing flowering in the shoot apical meristem of buds and growing tips.

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