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A Study of AK-01 in Solid Tumors

2017-03-28 23:38:22 | BioPortfolio

Summary

This two-part study consists of a Phase 1 dose escalation study in participants with locally advanced or metastatic solid tumors, and a Phase 2 portion in up to 3 cohorts with either Small Cell Lung Cancer, Breast Cancer and/or one other solid tumor type

Study Design

Conditions

Solid Tumor

Intervention

AK-01

Location

McGill University Health Centre
Montreal
Quebec
Canada
H4A 3J1

Status

Not yet recruiting

Source

AurKa Pharma Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-03-28T23:38:22-0400

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Medical and Biotech [MESH] Definitions

A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.

A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)

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