Magen Haim Project - Assessing Hand Hygiene Formulas

2017-06-16 01:38:25 | BioPortfolio


Background: Procedures of hand hygiene are an important component in prevention of cross-transmission of infections in hospitals. In recent years, hand washing with antiseptic soap (chlorhexidine) was replaced with use of alcohol-based hand rub. This change brought an increase in compliance with hand hygiene regulations from 30-40% to over 50%, and in other places up to 70%. However, even 70% compliance is not enough. One of the reported reasons for lack of compliance of staff to the use of alcohol-based preparations is skin irritation and dryness of the hands as a result of frequent use. At Sheba, like the majority of Israeli hospitals, the product used for handwashing is Septol (Teva), which includes 0.5% chlorhexidine gluconate (CHG) and 70% ethyl alcohol. The CDC, WHO and FDA guidelines approve for use of hospital hand hygiene, products that contain between 61-85% ethanol.

The investigators will replace the Septol currently used with a different alcohol-based antiseptic that is more user-friendly, and aim to determine whether this will increase the compliance with hand hygiene protocols.

The investigators will assess

1. Satisfaction of staff.

2. Increase of hand hygiene compliance.



Comparative research, Cross-Over, with a quasi-experimental component, comparing trial products to the use of Septol over the course of the year before the research.

Included in the study will be 29 departments of Sheba, whilst the other hospital departments will serve as a control group. The 29 departments will be divided into two branches with similar departments in each (each branch consisting of 3 internal medicine departments, 3 urgent care departments, a pediatric department, a surgical department, etc.). In Stage I (the initial six months), Branch A will exchange Septol with Avagard, and Branch B will exchange Septol with Softa-Man. In Stage II (the second six months), Branch A will change to Softa-Man and Branch B will change to Avagard. Branch C will be the control, where Septol will be used throughout the duration of the study.


For objectives 1 and 2: All medical staff at Sheba (in all 3 branches of the study).

Total: 15 Departments in Branch A, 14 Departments in Branch B

Stages of the Study:

1. At point zero (while still using Septol), distribute a questionnaire of hand hygiene compliance and satisfaction.

2. Instruction to Branch A and Branch B departments regarding the switch of Septol to the new product (instruction to staff in all sectors of these departments).

3. Exchange antiseptic Septol with the trial product in departments of Branch A and Branch B for the first six months (Stage I).

4. At point one (six months into the study), distribute a questionnaire of hand hygiene compliance and satisfaction.

5. Interim analysis of the questionnaires from point zero and point one.

6. Instruction to departments regarding the switch of products, regarding the use of the new product.

7. Exchange of trial product between the two groups for the second six month period (Stage II).

8. At point two (twelve months into the study), distribute a questionnaire of hand hygiene compliance and satisfaction.

9. Final analysis of questionnaires from Point 0, 1, and 2, as well as compliance of hand hygiene.

Study Design


Comparing Use of Hand Hygiene Products


Avagard-D (3M), Softa-Man (Braun), Septol


Sheba Medical Center


Not yet recruiting


Sheba Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2017-06-16T01:38:25-0400

Clinical Trials [842 Associated Clinical Trials listed on BioPortfolio]

A Two-week Crossover Evaluation of Two Hand Antiseptic Products on Skin Condition in Healthy Human Subjects

Evaluate the effect of two hand antiseptic products on hand skin conditions of healthy volunteers.

Simplifying the World Health Organization (WHO) Protocol for Hand Hygiene: me18Tschudin-Sutter

Non-inferiority in terms of reduction of bacterial counts will be investigated when combining the simpler three-step hand hygiene technique for the use of hand rub with a shorter applicati...

Helping Hands: Promoting Hand Hygiene in Hospital Nurses

Hand hygiene prescriptions are the most important measure in the prevention of hospital acquired infections. Yet compliance rates are generally below 50% of all opportunities for hand hygi...

A Randomized Controlled Trial of a School Disinfection and Hand Hygiene Program

The objective of the trial is to assess the impact of a disinfection and hand hygiene program on absenteeism in elementary school classrooms. Students in intervention classrooms will use ...

Effectiveness of an Alcohol-based Hand Rub to "Clean" Gloved Hands

Although little is known about compliance with the World Health Organization (WHO) 5 Moments of hand hygiene, the few existing studies report a high number of opportunities and compliance ...

PubMed Articles [6585 Associated PubMed Articles listed on BioPortfolio]

Sleep safe in clean hands: Improving hand hygiene compliance in the operating room through education and increased access to hand hygiene products.

Hand hygiene compliance is low among anesthesia providers in the operating room, which places patients at risk of preventable infections. The goal of this project was to improve hand hygiene complianc...

The influence of observational hand hygiene auditing on consultant doctors' hand hygiene behaviors: A qualitative study.

Compliance with hand hygiene guidelines reduces the risk of health care-associated infection, yet doctors are less compliant than other health care workers. Use of observational hand hygiene auditing ...

Implementation of a national quality improvement program to enhance hand hygiene in nursing homes in Taiwan.

This study investigated the cause of hand hygiene deficit, and further implemented a quality improvement program using WHO's hand-hygiene strategy to enhance the compliance of hand hygiene in the nurs...

Everybody hands-on to avoid ESKAPE: effect of sustained hand hygiene compliance on healthcare-associated infections and multidrug resistance in a paediatric hospital.

Hand hygiene is the most important strategy for preventing healthcare-associated infections (HCAIs); however, the impact of hand hygiene in middle-income countries has been poorly described. In this w...

Health Care Workers' Attitudes towards Hand Hygiene Monitoring Technology.

Automated Radio-Frequency Identification (RFID)-based hand hygiene monitoring technology has been implemented in an infectious disease department to study healthcare workers' (HCWs) practices and impr...

Medical and Biotech [MESH] Definitions

Practices involved in preventing the transmission of diseases by hand.

Personal care items used during MENSTRUATION.

Personal care items for women.

The practice of personal hygiene of the mouth. It includes the maintenance of oral cleanliness, tissue tone, and general preservation of oral health.

A combination of the debris index and the dental calculus index to determine the status of oral hygiene.

More From BioPortfolio on "Magen Haim Project - Assessing Hand Hygiene Formulas"

Quick Search


Relevant Topics

Food is any substance consumed to provide nutritional support for the body. It is usually of plant or animal origin, and contains essential nutrients, such as carbohydrates, fats, proteins, vitamins, or minerals. The substance is ingested by an organism ...

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...

Searches Linking to this Trial