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Neurophysiological Examination in Patients With Brain Death

2017-08-28 19:46:55 | BioPortfolio

Summary

This study examines muscle movements of elecromyography in adults with brain death. Half of the participants will have brain death, the other half will be healthy volunteers.

Description

In some of the patients who have brain death diagnosis, some movements may be seen. Because of these movements, the doctors sometimes avoid to make brain death diagnosis. So making brain death diagnosis may delay. And in these patients, even if the brain death diagnosis made the family members refuse to donate the organs of the patients because they think their patients may survive when they see muscle movements with touch. These patients with brain death are lost in a short time, so some of the patients can not be used as donors. In this study, the investigators aim to raise awareness the movements in brain death patients can be seen, to study the movements neurophysiologically by EMG, whether EMG can be used as auxiliary method or not in brain death diagnosis and to raise organ donation numbers from cadavers. Investigators will examine the motor response and F response in the facial nerve, median nerve, and tibialis posterior nerve with electromyography neurophysiologically.

Study Design

Conditions

Brain Death

Location

Yuzuncu Yil University, School of Medicine
Van
Tusba / Zeve Kampus
Turkey
65080

Status

Active, not recruiting

Source

Yuzuncu Yıl University

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-08-28T19:46:55-0400

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Medical and Biotech [MESH] Definitions

A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)

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The death of a FETUS of GESTATIONAL AGE 28 weeks or more, or the death of a live-born INFANT less than 28 days of age.

A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

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