Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients

2017-08-27 19:17:48 | BioPortfolio

Published on BioPortfolio: 2017-08-27T19:17:48-0400

Clinical Trials [723 Associated Clinical Trials listed on BioPortfolio]

Posaconazole Treatment of Invasive Fungal Infection (P05551)(COMPLETED)

A randomized, open label parallel controlled, multicenter study to evaluate safety and efficacy of Posaconazole oral suspension vs Fluconazole (capsule) in high-risk leukopenic patients f...

Optimized Diagnostics for Improved Therapy Stratification in Invasive Fungal Infections

Invasive fungal infections (IFI) in immunocompromised patients pose a major challenge for diagnostics designed to permit timely onset of appropriate treatment. The aim of the current clini...

A Retrospective Study Evaluating the Efficacy and Safety of Micafungin Sodium in the Treatment of Invasive Fungal Infections

The objective of this study is to evaluate the efficacy of intravenous micafungin for the empirical antifungal therapy, pre-emptive antifungal therapy, diagnostic driven antifungal therapy...

Registry of Patients Treated With Systemic Mold-Active Triazoles

The purpose of this study is to describe representative real-world patterns of care for the management of invasive fungal infections (IFIs), including invasive mold infection (IMI). Specif...

An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections

The objective of this study is to evaluate the efficacy, safety and toleration of voriconazole in the primary treatment of systemic or invasive fungal infections due to fungal pathogens fo...

PubMed Articles [18220 Associated PubMed Articles listed on BioPortfolio]

A Risk Prediction Model for Invasive Fungal Disease in Critically Ill Patients in ICU.

Developing a risk prediction model for invasive fungal disease based on an analysis of the disease related risk factors in critically ill patients of intensive care unit (ICU), in order to diagnose th...

Invasive Fungal Sinusitis: Risk Factors for Visual Acuity Outcomes and Mortality.

Invasive fungal sinusitis is a rare but potentially lethal disease that primarily affects immunocompromised patients. The purpose of this study was to review an academic medical center's experience in...

Conversion to Chronic Invasive Fungal Sinusitis From Allergic Fungal Sinusitis in Immunocompetence.

A review of the treatment of allergic and invasive fungal sinusitis, as well as a presentation of the first recorded case of a conversion from allergic fungal sinusitis (AFS) to chronic granulomatous ...

Epidemiology of invasive fungal infections in lung transplant recipients in Western Australia.

Invasive fungal infections (IFI) are common after lung transplantation with reported incidence at 12 months post-transplant of 8.1% to 16%, and 3-month all-cause mortality after IFI of 21.7%.

Validation of a multivariable prediction model for post-engraftment invasive fungal disease in 465 adult allogeneic hematopoietic stem cell transplant recipients.

Recently, we reported a simple prognostic score for post-engraftment invasive fungal disease (IFD) obtained in 404 adult allogeneic hematopoietic stem cell transplant (alloSCT) (training cohort).

Medical and Biotech [MESH] Definitions

An important nosocomial fungal infection with species of the genus CANDIDA, most frequently CANDIDA ALBICANS. Invasive candidiasis occurs when candidiasis goes beyond a superficial infection and manifests as CANDIDEMIA, deep tissue infection, or disseminated disease with deep organ involvement.

Suspensions of attenuated or killed fungi administered for the prevention or treatment of infectious fungal disease.

Mycoses which manifest as infections of deep tissue or blood.

Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.

Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.

More From BioPortfolio on "Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients"

Quick Search


Searches Linking to this Trial