Advertisement

Topics

Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients

2017-09-13 00:23:22 | BioPortfolio

Summary

Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability. Recently, more challenging approaches, such as stimulation of two or more sites or use of dual modality have been studied in stroke patients. In this study, simultaneous stimulation using both rTMS and tDCS (dual-mode stimulation) over bilateral primary motor cortices (M1s) was investigated to compare its modulatory effects with single rTMS stimulation in subacute stroke patients.

Description

We assessed each patient's motor function using the Fugl-Meyer Assessment (FMA) score and acquired their resting-state fMRI (rs-fMRI) data at two times: prior to stimulation and 2 months after stimulation. Changes in rs-fMRI network measures were investigated between groups.

Study Design

Conditions

Stroke

Intervention

rTMS on ipsilesional M1, tDCS on contralesional M1

Status

Completed

Source

Samsung Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-09-13T00:23:22-0400

Clinical Trials [2016 Associated Clinical Trials listed on BioPortfolio]

Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity

The investigators ultimate goal is to personalize brain stimulation for stroke so outcomes of the upper limb can be maximized for each individual patient. Several groups including the inve...

Association Between Brain Stimulations for the Rehabilitation of Chronic Stroke Patients

Cerebrovascular accident (CVA) is a cerebrovascular disease with high incidence and morbidity in the Brazilian population, and is considered a major cause of disability in adults. Brain da...

Dual Site-dual Channel Non-invasive Brain Stimulation for Motor Function in Stroke Patients

The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in post stroke patients. Simultaneous dual site-d...

Most Effective Stimulation Site in Transcranial Direct Current Stimulation for Gait Recovery After Stoke

The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke. All subjects will go through four con...

Anodal tDCS Over the Contralesional Hemisphere With Robotic Arm Training in Subacute Stroke Patients With Severe Upper Limb Hemiparesis

Upper limb recovery is not predicted by the initial severity of paralysis and the parameters reflecting the integrity of the corticospinal tract (e.g. motor evoked potential, fractional an...

PubMed Articles [1829 Associated PubMed Articles listed on BioPortfolio]

Neuroplasticity and network connectivity of the motor cortex following stroke: A transcranial direct current stimulation study.

Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has potential for clinical utility in neurorehabilitation. However, recent evidence indicates that the ...

Transcranial direct current stimulation and suppression of contralesional primary motor cortex post-stroke: a systematic review and meta-analysis.

The purpose of this systematic review and meta-analysis was to investigate the therapeutic effects of cathodal tDCS (ctDCS) that suppresses the contralesional primary motor cortex (cM1) activity for i...

Impact of clinical severity of stroke on the severity and recovery of visuospatial neglect.

There is growing evidence that visuospatial neglect (VSN) is associated with lower functional performance in other modalities and is not restricted to the lesioned hemisphere alone, and may also affec...

Abnormal Functional Connectivity Density in Post-Stroke Aphasia.

Post-stroke aphasia (PSA), which refers to the loss or impairment of language, is typically caused by left hemisphere lesions. Previous neuroimaging studies have indicated that the pathology of PSA ma...

Altered intra- and inter-network functional coupling of resting-state networks associated with motor dysfunction in stroke.

Motor functions are supported through functional integration across the extended motor system network. Individuals following stroke often show deficits on motor performance requiring coordination of m...

Medical and Biotech [MESH] Definitions

Restoration of functions to the maximum degree possible in a person or persons suffering from a stroke.

Stroke caused by lacunar infarction or other small vessel diseases of the brain. It features hemiparesis (see PARESIS), hemisensory, or hemisensory motor loss.

A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.

A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.

More From BioPortfolio on "Effects of Brain Network by Simultaneous Dual-mode Stimulation in Subacute Stroke Patients"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Neurology - Central Nervous System (CNS)
Alzheimer's Disease Anesthesia Anxiety Disorders Autism Bipolar Disorders Dementia Epilepsy Multiple Sclerosis (MS) Neurology Pain Parkinson's Disease Sleep Disorders Neurology is the branch of me...

Women's Health
Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...

Stroke - Cerebrovascular Disease (CVA)
A stroke is a serious medical condition that occurs when the blood supply to part of the brain is cut off. Strokes are a medical emergency and prompt treatment is essential because the sooner a person receives treatment for a stroke, the less damage is ...


Searches Linking to this Trial