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The overall aim is to investigate if circulating fatty acids and lipids are influenced by alterations in carbohydrate amount and quality.
In this isocaloric clinical cross-over trial, we aim to investigate if circulating fatty acids and lipids are influenced by alterations in carbohydrate amount and quality. We intend to evaluate if changes in carbohydrate quantity and quality (including sugar) influence circulating even-chain saturated fatty acids or if fatty acid-derived indices of desaturation and de novo lipogenesis are more sensitive biomarkers of carbohydrate intake. By performing untargeted lipidomic analyses, we aim to search for novel lipid biomarkers of carbohydrate quantity and quality. We also want to evaluate the influence of moderate alterations of carbohydrate and sugar intake on lipoproteins, insulin sensitivity, inflammatory proteins.
Low carbohydrate diet, High carbohydrate, high sugar diet, High carbohydrate, low sugar diet
Uppsala univeristy hospital
Published on BioPortfolio: 2017-09-28T04:38:22-0400
This study will examine the effects of a low carbohydrate diet versus a high carbohydrate diet on weight loss.
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A diet that consists mainly of foods with a high content of protein and limited amounts of CARBOHYDRATES.
A diet prescribed in the treatment of diabetes mellitus, usually limited in the amount of sugar or readily available carbohydrate. (Dorland, 27th ed)
A diet that contains limited amounts of CARBOHYDRATES. This is in distinction to a regular DIET.
A diet that includes foods with a high protein content.
A diet rich in DIETARY CARBOHYDRATES.
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