Topics

Influence of Carbohydrate on Amino Acid Absorption From Dietary Protein (ICADP)

2017-10-15 17:29:13 | BioPortfolio

Summary

10 young males will be recruited to participate in a randomized double blinded crossover study to investigate the influence of concomitant intake of two different types of carbohydrate with protein hydrolysate on the absorption kinetics of protein-derived amino acids and the impact on myofibrillar protein synthesis. During the trial days the subjects will perform a bout of whole body resistance exercise and ingest a supplement of meat hydrolysate labeled with D5-phenylalanine together with randomized and double blinded type of carbohydrate consisting of either glucose or cluster dextrin.

The primary outcome is the time to obtain peak concentration of D5-phenylalanine after intake of meat hydrolysate with either glucose or cluster dextrin.

Hypotheses:

I) The cluster dextrin will increase the absorption of the amino acids from the meat hydrolysate, and thereby result in a faster rise and a higher peak in plasma amino acid concentration in the postprandial period.

II) The meat hydrolysate will increase the protein synthesis rate to a higher extent when combined with cluster dextrin than with glucose.

Study Design

Conditions

Muscle Protein Synthesis

Intervention

Meat Hydrolysate, Cluster Dextrin, Placebo

Location

Bispebjerg Hospital
Copenhagen
Copenhagen NV
Denmark
2400

Status

Recruiting

Source

Bispebjerg Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-10-15T17:29:13-0400

Clinical Trials [2107 Associated Clinical Trials listed on BioPortfolio]

The Effect of a Protein Hydrolysate on Muscle Strength Recovery

Overtraining is a real problem for (semi-)professional athletes. Overtraining is often caused by the bodies' lack of ability to recover between training. In addition, during high intensity...

Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis

Muscle protein synthesis can be stimulated by ingestion of protein sources, such as whey, casein or soy. Protein supplementation can be useful to restore protein turnover after exercise bu...

Effect of Nutrition on Muscle Protein Synthesis

The present proposal is designed to examine the effect of carbohydrate and protein co-ingestion on muscle protein synthesis during endurance type exercise activities. We hypothesize that m...

Amino-acid Uptake After Meat Protein Intake

The purpose of the project is to provide evidence for the use of hydrolysed meat protein (HMP) as a protein supplement for elderly who has difficulty meeting the recommended daily protein ...

Skeletal Muscle Protein Synthesis: Traditional and Cluster Sets

Traditionally, when performing resistance exercise, repetitions are performed in a continuous manner resulting in a decrease in velocity, and thus power output. "Cluster" set is an alterna...

PubMed Articles [18957 Associated PubMed Articles listed on BioPortfolio]

Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial.

Muscle protein synthesis (MPS) can be stimulated by ingestion of protein sources, such as whey, casein, or soy. Protein supplementation can enhance muscle protein synthesis after exercise and may pres...

Acetylome profiling reveals extensive involvement of lysine acetylation in the conversion of muscle to meat.

Protein lysine acetylation is an post-translational modification that regulates gene expression, metabolism, cell signaling, and diseases, but its implication in the postmortem (PM) meat quality devel...

Differential regulation of protein synthesis by skeletal muscle type in chickens.

In mammalian skeletal muscles, protein synthesis rates vary according to fiber types. We herein demonstrated differences in the regulatory mechanism underlying the protein synthesis in the pectoralis ...

Revisiting the roles of protein synthesis during skeletal muscle hypertrophy induced by exercise.

Protein synthesis is deemed the underpinning mechanism enhancing protein balance required for skeletal muscle hypertrophy in response to resistance exercise. The current model of skeletal muscle hyper...

More room for legume - Consumer acceptance of meat substitution with classic, processed and meat-resembling legume products.

The substitution of meat with legumes is one way of making food consumption more sustainable. The substitution would ease the debate on food security and is aligned with the recommendations of climate...

Medical and Biotech [MESH] Definitions

Meat such as beef, pork, or lamb which contains more MYOGLOBIN than POULTRY or SEAFOOD.

The aggregate enterprise of technically producing packaged meat.

Hydrolysate of DNA in which purine bases have been removed.

A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.

More From BioPortfolio on "Influence of Carbohydrate on Amino Acid Absorption From Dietary Protein (ICADP)"

Quick Search

Relevant Topics

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Blood
Blood is a specialized bodily fluid that delivers necessary substances to the body's cells (in animals) – such as nutrients and oxygen – and transports waste products away from those same cells.  In vertebrates, it is composed of blo...


Searches Linking to this Trial