Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE)

2017-11-08 00:46:15 | BioPortfolio

Published on BioPortfolio: 2017-11-08T00:46:15-0500

Clinical Trials [12459 Associated Clinical Trials listed on BioPortfolio]

Transfusion of Biotinylated Red Blood Cells

The purpose of this research is to study how red blood cells (RBCs) survive in a person's circulation, and how that survival may be different in red blood cells that are donated and stored...

VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?

This is a single-center, randomized, partially blinded study to determine whether 42-day old red blood cells (RBCs) deliver oxygen as effectively as 7-day old RBCs and also to determine wh...

A Study to Assess the Recovery and Lifespan of Radiolabeled Autologous S 303 Treated Red Blood Cells

The objective of this study is to assess the post-infusion viability of S-303 Red Blood Cells (RBC) by measuring the 24 hour post-infusion recovery and lifespan of autologous RBCs prepared...

POOLED Red Blood Cells Prepared From Pooling 5 Leukoreduced, Irradiated RBC Units

The purpose of the study is to determine the safety of pooled red blood cells (RBCs) compared to standard leukoreduced RBC products stored in additive solution. The primary objective is to...

Frozen Red Blood Cell Transfusions in Trauma Patients

The purpose of this study is to look at red blood cell(RBC)transfusions in trauma patients and evaluate for any differences between the age of the RBCs and how they were stored. The invest...

PubMed Articles [31140 Associated PubMed Articles listed on BioPortfolio]

Altered Expression Levels of CD59, but not CD55, on Red Blood Cells in Stored Blood.

Red blood cells (RBCs) in storage undergo structural and biochemical changes that may cause functional effects. Studies exploring structural changes affecting the expression levels of CD55 and CD59 on...

Studying the rigidity of red blood cells induced by Plasmodium falciparum infection.

We study the effect of different chemical moieties on the rigidity of red blood cells (RBCs) induced by Plasmodium falciparum infection, and the bystander effect previously found. The infected cells a...

High-throughput 3D visualization of nanoparticles attached to the surface of red blood cells.

Blood circulation is the main distribution route for systemic delivery and the possibility to manipulate red blood cells (RBCs) by attaching nanoparticles to their surface provides a great opportunity...

Inhibition of Glutathione Synthesis via Decreased Glucose Metabolism in Stored RBCs.

Although red blood cells (RBCs) transfusions can be lifesaving, they are not without risk. RBCs storage is associated with the abnormal metabolism of glutathione (GSH), which may increase the risk of ...

Evaluation of the use of blood in surgeries as a tool to change patterns for requesting blood product reserves.

Thirty to sixty percent of prepared blood products are not transfused. Blood reserves for surgeries lead to many unused blood products, which increases hospital costs. The aim of this study is to iden...

Medical and Biotech [MESH] Definitions

The fraction of a blood sample, following CENTRIFUGATION, that is distinguished as a thin light-colored layer between the RED BLOOD CELLS, underneath it, and the PLASMA, above it. It is composed mostly of WHITE BLOOD CELLS and PLATELETS.

The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.

Specialized phagocytic cells of the MONONUCLEAR PHAGOCYTE SYSTEM found on the luminal surface of the hepatic sinusoids. They filter bacteria and small foreign proteins out of the blood, and dispose of worn out red blood cells.

A method to identify and enumerate cells that are synthesizing ANTIBODIES against ANTIGENS or HAPTENS conjugated to sheep RED BLOOD CELLS. The sheep red blood cells surrounding cells secreting antibody are lysed by added COMPLEMENT producing a clear zone of HEMOLYSIS. (From Illustrated Dictionary of Immunology, 3rd ed)

Transplantation of stem cells collected from the peripheral blood. It is a less invasive alternative to direct marrow harvesting of hematopoietic stem cells. Enrichment of stem cells in peripheral blood can be achieved by inducing mobilization of stem cells from the BONE MARROW.

More From BioPortfolio on "Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE)"

Quick Search


Searches Linking to this Trial