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Evaluation of a Closed Assisted Reproductive Technology (ART) Station Versus an Open Flow Cabinet

2017-11-22 05:06:13 | BioPortfolio

Summary

There is not yet a standardized system of human embryonic culture in vitro. In addition, technical improvements continually appear. The investigators recently carried out a study in which it shows that the grouped embryo culture at low oxygen tension (5% O2) in a benchtop incubator shows better success rates than individual culture at atmospheric oxygen tension (20% O2) in a conventional incubator. For these reasons, the investigators have decided to continue this research line to evaluate the efficacy of a new ART station with a closed environment in comparison of an open flow cabinet. This new system keeps a controled environment maintaining a carbon dioxide (CO2) concentration of 6% and a temperature of 37 degrees. A prospective randomized study will be carried out in which the manipulation of the gametes and pre-embryos of the patients will be carried out in open laminar flow cabinets or in a closed station that maintain the CO2 and temperature conditions.

Study Design

Conditions

ART

Intervention

Embryo handling in a closed station

Location

IVI Sevilla
Seville
Spain
41011

Status

Recruiting

Source

IVI Sevilla

Results (where available)

View Results

Links

Published on BioPortfolio: 2017-11-22T05:06:13-0500

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Medical and Biotech [MESH] Definitions

The environment outside the earth or its atmosphere. The environment may refer to a closed cabin (such as a space shuttle or space station) or to space itself, the moon, or other planets.

Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures.

The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.

Process for deciding utilization or disposal of an embryo that is fertilized but not immediately transplanted and resulting course of action.

The techniques used to select and/or place only one embryo from FERTILIZATION IN VITRO into the uterine cavity to establish a singleton pregnancy.

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