Treating Emotional Processing Impairments in Individuals With TBI

2017-12-20 10:17:08 | BioPortfolio


The current project will examine the impact of an emotional processing intervention on emotional processing abilities in a sample of 50 persons with moderate to severe TBI. Outcome will be assessed across 3 domains. We will document changes resulting from treatment: (1) in emotional processing tasks (2) in other areas of function including QOL, social functioning, mood and cognition that are also likely to be impacted (3) in brain structure and function. The examination of efficacy in the above three areas will further our knowledge of emotional processing deficits in TBI and more importantly, identify an effective means of treating such deficits.


Emotional processing deficits have a significant negative impact on the lives of persons with TBI. There is emerging research indicating that, in addition to cognitive and behavioral impairments, social and emotional difficulties following TBI are common and are related to significant problems in social relationships, poor social participation, impaired empathy, and a high degree of caregiver stress. Emotional processing is a critical component of social cognition, including the abilities to both identify and discriminate basic universal emotions. The stability of emotional processing deficits following TBI indicates that these impairments likely impact individuals with TBI consistently across the lifespan, and do not appear to resolve with time.

The goals of the trial are to (a) Evaluate the effectiveness of an emotional processing intervention to improve performance on tests of emotional processing in individuals with TBI, (b) Evaluate the improvement of secondary outcomes of psychological, cognitive, and functional abilities following the emotional processing intervention in individuals with TBI, (c) To examine differences in brain activation patterns during emotional processing following treatment in individuals with TBI, BOLD activation in the experimental group will be compared to BOLD patterns of the control group during performance of the QFDT, a facial affect recognition task.

Study Design


Traumatic Brain Injury


Emotional Processing Training, Placebo Control Exercises


Kessler Foundation
East Hanover
New Jersey
United States




Kessler Foundation

Results (where available)

View Results


Published on BioPortfolio: 2017-12-20T10:17:08-0500

Clinical Trials [5876 Associated Clinical Trials listed on BioPortfolio]

Remediation of Emotional Processing Deficits in MS

This study will test the effectiveness of an emotional processing intervention in individuals with MS in a double blind placebo controlled randomized clinical trial. We will utilize an int...

Speed of Processing Training in Traumatic Brain Injury

The purpose of this project is to test the hypothesis that Speed of Information Processing (SIP) deficits in acquired brain injury (ABI) can be remediated. The majority of individuals with...

Applying Speed of Processing Training to Individuals With Traumatic Brain Injury

This pilot study will document the efficacy of a behavioral intervention for Processing Speed (PS) in Traumatic Brain Injury (TBI), Speed of Processing Training (SPT), which has been succe...

Affect Recognition: Enhancing Performance of Persons With Traumatic Brain Injury (TBI)

The purpose of this research is to evaluate the effectiveness of three training programs designed to teach persons with traumatic brain injury to recognize emotions. It is hypothesized th...

MINDSpeed Food and Brain Training RCT

The purpose of this study is to learn how foods high in polyphenols and brain training exercises affect older adults' cognitive performance

PubMed Articles [22040 Associated PubMed Articles listed on BioPortfolio]

A quasi-experimental study examining the effects of online traumatic brain injury professional development on educator knowledge, application, and efficacy in a practitioner setting.

Each year ∼700 000 U.S. children ages 0-19 years sustain a traumatic brain injury. Children who experience brain injury are at risk for impairments in executive function, processing speed, cogn...

Adaptive cognitive control attenuates the late positive potential to emotional distractors.

Emotional pictures are inherently prioritized during stimulus perception. While this preferential emotion processing promotes self-preservation and survival, it can be detrimental when it conflicts wi...

Neurophysiological evidences of the transient effects of mindfulness induction on emotional processing in children: An ERP study.

Mindfulness has been shown to improve mental health through adaptive responses during emotional processing. Although the benefits of mindfulness and the corresponding neural correlates have been demon...

The local properties of bold signal fluctuations at rest monitor inhibitory control training in adolescents.

Inhibitory control (IC) plays a critical role in cognitive and socio-emotional development. Short-term IC training improves IC abilities in children and adults. Surprisingly, few studies have investig...

How is your mind-set? Proof of concept for the measurement of the level of emotional development.

In persons with intellectual and developmental disabilities, not only cognitive brain functions, but also socio-emotional processing networks may be impaired. This study aims to validate the Scale of ...

Medical and Biotech [MESH] Definitions

Bleeding within the brain as a result of penetrating and nonpenetrating CRANIOCEREBRAL TRAUMA. Traumatically induced hemorrhages may occur in any area of the brain, including the CEREBRUM; BRAIN STEM (see BRAIN STEM HEMORRHAGE, TRAUMATIC); and CEREBELLUM.

Technique based on muscle relaxation during self-hypnotic exercises. It is used in conjunction with psychotherapy.

A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.

Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.

A technique to self-regulate brain activities provided as a feedback in order to better control or enhance one's own performance, control or function. This is done by trying to bring brain activities into a range associated with a desired brain function or status.

More From BioPortfolio on "Treating Emotional Processing Impairments in Individuals With TBI"

Quick Search

Relevant Topics

Mental Health
Adhd Anorexia Depression Dyslexia Mental Health Psychiatry Schizophrenia Stress Mental health, although not being as obvious as physical health, is very important, causing great unhappiness to those affected, causing add...

Anxiety Disorders
Anxiety is caused by stress. It is a natural reaction, and is beneficial in helping us deal with tense situations and pressure. It is deterimental when is becomes an excessive, irrational dread of everyday situations. The most common types of anxiety di...

Searches Linking to this Trial