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Study for Optimizing Anti-inflammatory Prophylaxis

2018-01-04 13:08:11 | BioPortfolio

Published on BioPortfolio: 2018-01-04T13:08:11-0500

Clinical Trials [2536 Associated Clinical Trials listed on BioPortfolio]

Adherence to Gastro-Protection in Non-Steroidal Anti-Inflammatory Drug (NSAID) Using Patients

Prospective multicentric study to evaluate the compliance of gastroprotective treatment in NSAID patients at risk of GI complications. Secondary objectives: To identify the factors associa...

Efficiency Study About the Effect of Acupuncture on Postoperative Pain After Total Knee Arthroplasty

The purpose of this study is to evaluate the use of needle acupuncture in comparison to a conventional postoperative pain management in terms of reducing pain and pain medication use in an...

Esomeprazole And Symptomatic Response In Patients With Or Without An Elevated Risk For Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated GI Damage

The purpose of this study is to compare the treatment effect in patients with upper gastro-intestinal complaints with an elevated risk for NSAID-associated GI-damage to those without an el...

A Randomized, Double-blind, Placebo-controlled Multicenter Study of Secukinumab (AIN457) to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing Spondylit

The current study will assess the clinical Assessment of SpondyloArthritis international Society (ASAS) 20 response to Secukinumab and evaluate to which extent concomitant nonsteroidal ant...

Cobiprostone Prevention of NSAID-induced Gastroduodenal Injury

The primary purpose of this study is to determine the efficacy and safety of three dose levels of cobiprostone as compared to placebo in OA/RA patients treated with an NSAID.

PubMed Articles [2842 Associated PubMed Articles listed on BioPortfolio]

Non-Steroidal Anti-Inflammatory Drug (NSAID) Prescriptions from the 6 Month of Pregnancy: Impact of Advice from Health Authorities.

NSAIDs are among the most widely used drugs. On June 2008 and February 2009, Dear Doctor Letters (DDLs) were sent by the French Health Authorities (AFSSAPS) to remind practitioners of risks with NSAID...

Associations between TMEM196 polymorphisms and NSAID-exacerbated respiratory disease in asthma.

We previously found differences in the minor allele frequency (MAF) of single-nucleotide polymorphisms (SNPs) in transmembrane protein 196 (TMEM196) between 995 patients with aspirin-tolerant asthma (...

Nonsteroidal Antiinflammatory Drug Administration and Postpartum Blood Pressure in Women With Hypertensive Disorders of Pregnancy.

To evaluate whether postpartum nonsteroidal antiinflammatory drug (NSAID) administration is associated with increased blood pressure in women with hypertensive disorders of pregnancy and to estimate t...

NSAID choice: lessons from PRECISION.

The role of misclassification of exposure in the association between aspirin and non-steroidal anti-inflammatory drug use and keratinocyte cancers.

We read with interest the recently published paper by Pandeya et al. , which assessed the association between aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) and incident keratinocyte canc...

Medical and Biotech [MESH] Definitions

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.

A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.

A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)

A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.

A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

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