Safety, Reactogenicity, and Immunogenicity of mRNA-1653 in Healthy Adults

2018-01-16 09:55:10 | BioPortfolio


This clinical study will assess the safety, reactogenicity and immunogenicity of mRNA-1653, a combined human metapneumovirus and human parainfluenza virus type 3 vaccine in healthy adults.

Study Design


Human Metapneumovirus and Human Parainfluenza Infection


mRNA-1653, Placebo


Meridian Clinical Research, LLC
United States




Moderna Therapeutics

Results (where available)

View Results


Published on BioPortfolio: 2018-01-16T09:55:10-0500

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Medical and Biotech [MESH] Definitions

A genus of the subfamily PNEUMOVIRINAE, containing two members: Turkey rhinotracheitis virus and a human Metapneumovirus. Virions lack HEMAGGLUTININ and NEURAMINIDASE.

An acute inflammatory disease of the upper RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

Vaccines or candidate vaccines used to prevent infection with parainfluenza viruses in humans and animals.

A species of RESPIROVIRUS frequently isolated from small children with pharyngitis, bronchitis, and pneumonia.

A species of RUBULAVIRUS associated particularly with acute laryngotracheitis (CROUP) in children aged 6 months to 3 years.

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