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Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts

2018-01-30 13:26:13 | BioPortfolio

Summary

Patients with advanced chronic liver disease may develop hypertension of the portal vein, which is the main cause for most complications and deaths of patients with liver cirrhosis. Implantation of a transjugular intrahepatic portosystemic shunt (TIPS) leads to instantaneous alleviation of portal hypertension, but may cause confusion or even lead to hepatic coma. Stents, as well as patient stratification and medical surveillance, have drastically improved over the past decades. However, there are few data on long-term effects on hemodynamics and clinical outcome after TIPS implantation.

In this prospective registry study, we want to observe the clinical course of patients after undergoing TIPS intervention. We want to assess effectiveness, hemodynamic changes and risk of developing complications after TIPS in order to improve post-interventional surveillance and patient outcome.

Study Design

Conditions

Portal Hypertension

Intervention

Observational study

Location

Medical University of Vienna
Vienna
Austria
1090

Status

Recruiting

Source

Medical University of Vienna

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-01-30T13:26:13-0500

Clinical Trials [2138 Associated Clinical Trials listed on BioPortfolio]

Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatin

Portal hypertension is not a disease in itself. Rather, it is an indication of an illness, caused mostly by chronic lesions of the liver because of distinct causes, such as viral infection...

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This study evaluates correlation in changes of HVPG-pressure values and stiffness values (ARFI) for spleen and liver and flow-volume values in Portal vein in patients with liver cirrhosis/...

PubMed Articles [12242 Associated PubMed Articles listed on BioPortfolio]

Low-free triiodothyronine is associated with poor prognosis of portal hypertension in cirrhosis.

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von Willebrand factor as a biomarker of clinically significant portal hypertension and severe portal hypertension: a systematic review and meta-analysis.

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Non-invasive assessment of portal hypertension by multi-parametric magnetic resonance imaging of the spleen: A proof of concept study.

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Medical and Biotech [MESH] Definitions

Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).

Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).

Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.

A work that reports on the results of a clinical study in which participants may receive diagnostic, therapeutic, or other types of interventions, but the investigator does not assign participants to specific interventions (as in an interventional study).

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