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Expanded Access Use of Tucatinib for HER2+ Metastatic Breast Cancer

2018-02-12 17:45:11 | BioPortfolio

Published on BioPortfolio: 2018-02-12T17:45:11-0500

Clinical Trials [7 Associated Clinical Trials listed on BioPortfolio]

A Study of the Absorption, Metabolism, and Excretion of Tucatinib in Healthy Participants

This study will look at how a drug (tucatinib) leaves the body and what happens to tucatinib while it is still in the body. Healthy participants will get one dose of tucatinib by mouth. Pa...

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

This study is being done to look at how tucatinib could affect the way other drugs work. This study will look at healthy volunteers and how tucatinib affects their liver enzymes. Liver enz...

Tucatinib (ONT-380) and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer (MOUNTAINEER)

This is a phase II trial that will study how well tucatinib (ONT-380) and trastuzumab work in treating patients with colorectal cancer with a specific genetic marker (human epidermal growt...

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

A phase 2 non-randomized study to assess the safety and efficacy of the combination of tucatinib and trastuzumab with capecitabine for the treatment of leptomeningeal metastases in HER2-ne...

Effects of Tucatinib on Cardiac Repolarization in Healthy Participants

This study is looking at how the study drug, tucatinib, affects the heart. Tucatinib is being studied as a possible treatment for breast cancer. This study will recruit healthy volunteers....

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