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Effects of Antirheumatic Treatment on Levels of Survivin in Rheumatoid Arthritis Patients

2018-02-26 20:24:12 | BioPortfolio

Summary

To validate the utility of survivin as a biomarker of pharmacological response to therapeutic intervention in rheumatoid arthritis patients.

Description

In a prospective observational study the investigators aim to study the ability of modern antirheumatic treatments to suppress levels of survivin in sera. Rheumatoid arthritis patients scheduled to start new pharmacological treatment will be followed for a period of 6 months. No intervention or influence on choice of treatment will be performed, the decision of new/other medication is entirely made by the patient and their rheumatologist. The study entails addition of survivin analyse (1 vial of sera) before and after start of new treatment. Data concerning survivin levels, disease activity and other clinical parameters before and after start of new treatment will also be analysed. The patients will leave sera for survivin analyse at baseline and 3 and 6 months after start of new treatment.

Study Design

Conditions

Rheumatoid Arthritis

Intervention

methotrexate, sulfasalazine, abatacept, tocilizumab, tofacitinib/baricitinib

Location

Dept of Rheumatology and Inflammation research
Gothenburg
Sweden

Status

Recruiting

Source

Vastra Gotaland Region

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-02-26T20:24:12-0500

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