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Next-generation Sequencing in Gastric Cancer to Evaluation Prognosis

2018-03-29 03:17:22 | BioPortfolio

Summary

Liquid biopsy has been widely used in the diagnosis and treatment of tumors, and cfDNA has always been a hot spot in clinical research. Previous studies have shown that cfDNA may be associated with postoperative recurrence of gastric cancer, but it is rarely reported whether cfDNA is associated with the survival of gastric cancer. The purpose of this study was to assess the relationship between cfDNA and survival in advanced gastric cancer

Description

Liquid biopsy has been widely used in the diagnosis and treatment of tumors, and cfDNA has always been a hot spot in clinical research. Previous studies have shown that cfDNA may be associated with postoperative recurrence of gastric cancer, but it is rarely reported whether cfDNA is associated with the survival of gastric cancer. The purpose of this study was to assess the relationship between cfDNA and survival in advanced gastric cancer

Study Design

Conditions

Gastric Cancer

Intervention

High cfDNA Group

Location

Rongbo Lin
Fuzhou
Fujian
China
350014

Status

Recruiting

Source

Fujian Cancer Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-03-29T03:17:22-0400

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Medical and Biotech [MESH] Definitions

That portion of the stomach remaining after gastric surgery, usually gastrectomy or gastroenterostomy for cancer of the stomach or peptic ulcer. It is a common site of cancer referred to as stump cancer or carcinoma of the gastric stump.

A proto-oncogene protein and member of the Wnt family of proteins. It is frequently up-regulated in human GASTRIC CANCER and is a tumor marker (TUMOR MARKERS, BIOLOGICAL) of gastric and COLORECTAL CANCER.

A deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.

A tumor of both low- and high-grade malignancy. The low-grade grow slowly, appear in any age group, and are readily cured by excision. The high-grade behave aggressively, widely infiltrate the salivary gland and produce lymph node and distant metastases. Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. They are the most common malignant tumor of the parotid. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575; Holland et al., Cancer Medicine, 3d ed, p1240)

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

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