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The Markers and Paracetamol Poisoning Study 2

2018-04-20 09:47:10 | BioPortfolio

Published on BioPortfolio: 2018-04-20T09:47:10-0400

Clinical Trials [975 Associated Clinical Trials listed on BioPortfolio]

PP100-01 (Calmangafodipir) for Overdose of Paracetamol

Investigate the safety and tolerability of PP100-01 add-on treatment to the 12hr NAC treatment regime in patients treated for paracetamol/acetaminophen overdose (POD) when NAC treatment is...

EVALUATION OF THE RELATIONSHIP BETWEEN EFFERVESCENT PARACETAMOL AND BLOOD PRESSURE. CLINICAL TRIAL.

Paracetamol's solubility is achieved by adding to the excipient sodium salts, either as bicarbonate, carbonate or citrate. As the relationship between salt and hypertension is well known, ...

Macrophage Markers, Soluble CD163 (sCD163) and Soluble CD206 (sCD206) in Paracetamol Overdose

Paracetamol (PCM) is a widely used over-the-counter analgesic, and overdose with PCM is a condition regularly seen in everyday clinical practice. Identification of the patients with early ...

Drug Interaction Between Paracetamol and Warfarin

The objective of this study is to investigate whether paracetamol, given at therapeutic doses (2g/day and 3 g/day), may potentiate the anticoagulant effect of warfarin.

Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination

The purpose of this study is to determine whether the combination of paracetamol (acetaminophen) and other NSAIDs with or without weak opioids can give synergistic analgesic effect.

PubMed Articles [9499 Associated PubMed Articles listed on BioPortfolio]

Effect of effervescent paracetamol on blood pressure: a crossover randomized clinical trial.

To evaluate the effect of effervescent paracetamol on office and ambulatory blood pressure (BP) compared with noneffervescent paracetamol in hypertensive patients.

Paracetamol-induced liver injury modelled in Xenopus laevis embryos.

Failure to predict drug-induced liver injury (DILI) remains a major contributing factor to lead compound drop-out during drug development. Xenopus embryos are amenable for early stage medium throughpu...

Fewer adverse effects associated with a modified two-bag intravenous acetylcysteine protocol compared to traditional three-bag regimen in paracetamol overdose.

The intravenous (IV) N-acetylcysteine (NAC) regimen used worldwide in paracetamol overdose is complex with three separate weight-based doses and is associated with a high incidence of adverse events i...

An insight into paracetamol and its metabolites using molecular docking and molecular dynamics simulation.

Paracetamol is a relatively safe analgesia/antipyretic drug without the risks of addiction, dependence, tolerance, and withdrawal when used alone. However, when administrated in an opioid/paracetamol ...

Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability.

Paracetamol is the analgesic most used by older people. The physiological changes occurring with ageing influence the pharmacokinetics (PK) of paracetamol and its variability. We performed a populatio...

Medical and Biotech [MESH] Definitions

Laboratory tests for evaluating the individual's clotting mechanism.

Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.

Laboratory tests demonstrating the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease.

Blood tests used to evaluate the functioning of the thyroid gland.

Serological tests that measure anti-hemadsorption agents such as antiviral ANTIBODIES that block VIRAL HEMAGGLUNININS from adhering to the surface of red blood cells.

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