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National Institute for Health Research (NIHR) Health Informatics Collaborative Troponin Study

2018-05-02 14:06:12 | BioPortfolio

Published on BioPortfolio: 2018-05-02T14:06:12-0400

Clinical Trials [101 Associated Clinical Trials listed on BioPortfolio]

Angioplasty to Blunt the Rise of Troponin in Acute Coronary Syndrome (ACS)

Release of troponin evaluated by the peak of troponin during the hospital phase.Because of its sensitivity and specificity as well as its widespread use in routine practice, rise in tropo...

Troponin Elevation in the Elderly Patient With Hip Fracture

Elevated troponin is powerful and independent adverse prognostic marker in patient with ACS. However, non specific (non cardiac) troponin elevation is a common finding among hospitalized p...

Variations of High Sensitivity Troponin T in Neonates

Troponin T-us is a cardiac marker for myocardial infarction. Its use in neonates is increasing, yet normal values are still to be determined for the latest generation of tests, such as Hig...

Postoperative Troponin in Renal Dysfunction After Cardiac Surgery

Elevated level of troponin is frequently observed among patients with renal dysfunction. Increase in troponin after cardiac surgery may predict postoperative outcome in cardiac surgery pat...

Sensitive Troponin I in Out-of-hospital Cardiac Arrest

Troponin is a major diagnostic criterion of acute myocardial infarction (AMI) which confirms myocardial damage and necrosis. In out-of-hospital cardiac arrest (OHCA) patients its dynamics ...

PubMed Articles [160 Associated PubMed Articles listed on BioPortfolio]

The importance of low level QC for high sensitivity troponin assays.

With the advent of the new high-sensitivity troponin assays, it is becoming critical to measure troponin accurately to low concentrations. To ensure assay performance is acceptable, appropriate QC mus...

Evaluation of sex-specific cut-off values of high-sensitivity cardiac troponin I and T assays in an emergency department setting - Results from the Linz Troponin (LITROP) study.

The aim of the present analysis was to evaluate sex-specific cut-off values of a high-sensitivity cardiac troponin T (hs-cTnT) assay and a high-sensitivity cardiac troponin I (hs-cTnI) assay in an eme...

Peak Troponin I Levels Are Associated with Functional Outcome in Intracerebral Hemorrhage.

Troponin I is a widely used and reliable marker of myocardial damage and its levels are routinely measured in acute stroke care. So far, the influence of troponin I elevations during hospital stay on ...

Troponin testing in the emergency department: How should we take elevated troponin levels into consideration?

Circulating Troponin I Level in Patients with Acute Ischemic Stroke.

Cardiac troponin levels in the blood are an important biomarker of acute coronary events, but may also be elevated in the context of acute ischemic stroke without an obvious concurrent myocardial insu...

Medical and Biotech [MESH] Definitions

One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.

One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.

One of the three polypeptide chains that make up the TROPONIN complex of skeletal muscle. It is a calcium-binding protein.

One of the minor protein components of skeletal muscle. Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.

A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless its position is modified by TROPONIN.

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