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Implementing an IPTS Treatment Approach to Improve Outcomes in Suicidal Youth

2018-05-22 18:49:10 | BioPortfolio

Published on BioPortfolio: 2018-05-22T18:49:10-0400

Clinical Trials [158 Associated Clinical Trials listed on BioPortfolio]

Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

This is a randomized, double-blind, placebo-controlled study of the investigational drug uridine as a treatment for suicidal ideation in veterans. The investigators hypothesize that the a...

NRX100 vs. Placebo for Stabilization of Acute Suicidal Ideation an Behavior in Bipolar Depression

NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketam...

NeuroRx Sequential Therapy for Patients With Severe Bipolar Depression and Suicidal Ideation

NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketam...

NRX101 for Moderate Bipolar Depression and Suicidal Ideation

NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed NRX-101 (fixed dose combination of D-cycloserine and...

Positive Psychology in Suicidal Patients

Suicide is a major health concern. Weeks following psychiatric admission are a highly suicide risk period for those having current suicidal ideation or attempt. Recently, a pilot study sug...

PubMed Articles [332 Associated PubMed Articles listed on BioPortfolio]

MiR-29 family members interact with SPARC to regulate glucose metabolism.

MicroRNA (miR)-29 family members have been reported to play important regulatory roles in metabolic disease. We used TargetScan to show that "secreted protein acidic rich in cysteine" (SPARC) is a tar...

Summary of expression of SPARC protein in cutaneous vascular neoplasms and mimickers.

Serum protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein, which regulates cell proliferation and facilitates intracellular transport of albumin bound particles including chemo...

A fragment of SPARC reflecting increased collagen affinity shows pathological relevance in lung cancer - implications of a new collagen chaperone function of SPARC.

The matricellular protein SPARC (secreted proteome acidic and rich in cysteine) is known to bind collagens and regulate fibrillogenesis. Cleavage of SPARC at a single peptide bond, increases the affin...

Correlates of Suicidal Ideation During Pregnancy and Postpartum Among Women Living with HIV in Rural South Africa.

In developing countries, up to 20% of maternal deaths during pregnancy are due to suicide, and being HIV-infected confers additional risk. This manuscript sought to identify perinatal correlates of su...

Increased Macrophage-derived SPARC Precedes Collagen Deposition in Myocardial Fibrosis.

Myocardial fibrosis and the resultant increases in LV stiffness represent pivotal consequences of chronic pressure-overload (PO) that impact both functional capacity and the rates of morbid and mortal...

Medical and Biotech [MESH] Definitions

A risk factor for suicide attempts and completions, it is the most common of all suicidal behavior, but only a minority of ideators engage in overt self-harm.

Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.

Suicidal death of ERYTHROCYTES which results in features typical of apoptotic nucleated cells such as cell shrinkage, membrane blebbing, and scrambling of cell membrane to expose membrane PHOSPHATIDYLSERINES, which triggers engulfment and degradation by MACROPHAGES.

A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia.

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