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The purpose of this study is to understand the effects of using a Artificial Intelligence algorithm for skeletal age estimation as a computer-aided diagnosis (CADx) system. In this prospective real-time study, the investigators will send de-identified hand radiographs to the Artificial Intelligence algorithm and surface the output of this algorithm to the radiologist, who will incorporate this information with their normal workflows to make a diagnosis of the patient's bone age. All radiologists involved in the study will be trained to recognize the surfaced prediction to be the output of the Artificial Intelligence algorithm. The radiologists' diagnosis will be final and considered independent to the output of the algorithm.
The investigators are targeting to study the effect of their Artificial Intelligence algorithm on the radiologists' estimation of skeletal age. Currently, radiologists make the estimation using only the patients' radiographic images and health records. As part of this study, the radiologists will make diagnoses about their patients using the patients' radiographic images, health records, and the output of the CADx algorithm. The investigators wish to understand how radiologists using the Artificial Intelligence algorithm compare to radiologists who do not for the specific task of estimating skeletal age.
This study is organized as a multi-institutional randomized control trial with two arms - experiment (receiving the Artificial Intelligence algorithm's output) and control (no intervention). Both of these arms will be compared to a clinical reference standard ("gold standard") composed of a panel of radiologists. The metric of comparison will be Mean Absolute Distance (MAD) and Root-Mean-Square (RMS) error. The investigators plan to use statistical tests such as the t-test to determine any statistically-significant difference in skeletal age estimation between the two groups.
The investigators hope to recruit and analyze data from a sample size of 1000 patients.The patients will not undergo any research procedures that deviate from the current standard practices.
Not yet recruiting
Published on BioPortfolio: 2018-05-23T19:36:11-0400
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The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.
Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES.
A type of osseous tissue which makes up the inner part of bone. It has a spongy, honeycomb-like structure with struts or trabecula and contains the BONE MARROW. It has higher rate of BONE REMODELING turnover than CORTICAL BONE.
Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.
A carpal bone with a rounded head located between the TRAPEZOID BONE and the HAMATE BONE.
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