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COrticosteroids in acUte uRticAria in emerGency dEpartment

2018-06-11 01:09:10 | BioPortfolio

Summary

To demonstrate the non-inferiority of the efficacy of a single antihistamine in comparaison with an association of antihistamine and corticosteroid in the treatment of acute urticaria in emergency departments

Description

Acute urticaria (hives) is a common skin disease. The prevalence of acute urticaria in life is about 15 to 20% in the general population. It is responsible for a frequent use of emergency departments (ED). The usual treatment is based on early administration of an association of antihistamines and corticosteroid. The therapeutic efficacy of corticosteroids has never been established by high evidence studies. However, corticosteroids are frequently used. When stopped, corticosteroids could promote the occurence of urticaria recurrences, and a transition to chronic urticaria. In addition, corticosteroids may be rarely responsible for gastrointestinal bleeding, hypertension and diabetes.

Study Design

Conditions

Urticaria

Intervention

Placebo Oral Tablet, Cortancyl Oral Tablet, Levocetirizine Oral Tablet

Location

Hospital Louis MOURIER
Colombes
Ile De France
France
92700

Status

Not yet recruiting

Source

Assistance Publique - Hôpitaux de Paris

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-06-11T01:09:10-0400

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