PheWAS of a Polygenic Predictor of Thyroid Function

2018-07-27 13:22:12 | BioPortfolio


Performing a phenome-wide association study (PheWAS) identifying clinical diagnoses associated with a polygenic predictor of Thyroid stimulating hormone (TSH) levels identified by a previously published genome-wide association study (GWAS). PheWAS will be applied in an electronic-health-record (EHR) cohort including North American (n: 37,154) and European participants using 1,318 phenotypes.


Applying a genetic predictor of thyroid stimulating hormone levels to an electronic-health-record cohort to verify associations with thyroid disorders as positive controls, and identify new associations .

Study Design




phenome-wide association study (PheWAS)


AP-HP, Pitié-Salpêtrière Hospital, Department of Pharmacology, CIC-1421, Pharmacovigilance Unit, INSERM




Groupe Hospitalier Pitie-Salpetriere

Results (where available)

View Results


Published on BioPortfolio: 2018-07-27T13:22:12-0400

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