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Sleep Quality After Nasosinusal Surgery in AERD Patients

2018-08-15 18:45:12 | BioPortfolio

Published on BioPortfolio: 2018-08-15T18:45:12-0400

Clinical Trials [2631 Associated Clinical Trials listed on BioPortfolio]

Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease

Aspirin-Exacerbated Respiratory Disease, or AERD, consists of aspirin sensitivity, asthma and nasal polyps. It is currently managed by chronic steroid use, multiple endoscopic sinus surge...

Dupilumab for Aspirin-exacerbated Respiratory Disease

Subjects with physician-diagnosed aspirin-exacerbated respiratory disease (AERD) who remain unacceptably symptomatic with a SNOT 22 score > 18 despite routine medical therapy will be enrol...

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

The overall aim of the study is to determine the efficacy of oral ifetroban, a novel antagonist of T prostanoid (TP) receptors, as a treatment for patients with aspirin-exacerbated respira...

Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)

The purpose of this phase 2 study is to assess the safety and efficacy of oral ifetroban for the treatment of aspirin-exacerbated respiratory disease (AERD). AERD is a disease that involve...

Trial to Determine the Safety of Oral Ifetroban in Patients With a History of Aspirin Exacerbated Respiratory Disease

The primary objective of the study is to determine the safety of oral ifetroban compared to placebo as measured by a > 20% decrease in FEV1 compared to baseline following a dose of Investi...

PubMed Articles [28015 Associated PubMed Articles listed on BioPortfolio]

Sinus surgery is associated with a decrease in aspirin-induced reaction severity in AERD patients.

Nasal polyps influence the burden of aspirin exacerbated respiratory disease (AERD) by contributing to eicosanoid production. AERD is diagnosed through graded aspirin challenges. It is not known how s...

Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease (AERD).

Plasma tryptase elevation during aspirin-induced respiratory reactions occurs in 50% of reactions despite CysLTR antagonist prophylaxis and identifies lung function decline and extra-respiratory sympt...

Comparable safety of two aspirin desensitization protocols for aspirin exacerbated respiratory disease (AERD).

Accidental ingestion of aspirin and non-steroidal anti-inflammatory drugs is common in patients with aspirin-exacerbated respiratory disease.

Epithelial Folliculin Enhances Airway Inflammation in Aspirin-Exacerbated Respiratory Disease.

Clinical features of aspirin-exacerbated respiratory disease (AERD) are characterized by overproduction of cysteinyl leukotrienes (LT) and eosinophil activation, in which epithelial cells contribute t...

Medical and Biotech [MESH] Definitions

A specialized form of transanal endoscopic surgery for microscopically controlled operations in the RECTUM.

Endoscopic surgical procedures performed with visualization via video transmission. When real-time video is combined interactively with prior CT scans or MRI images, this is called image-guided surgery (see SURGERY, COMPUTER-ASSISTED).

A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)

Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.

Endoscopic surgery of the pleural cavity performed with visualization via video transmission.

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