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Cefepime/AAI101 Phase 2 Study in Hospitalized Adults With cUTI

2018-09-27 07:04:18 | BioPortfolio

Summary

Phase 2, randomised, double-blind, 2-cohort study in hospitalised adults with complicated urinary tract infection (cUTI), including acute pyelonephritis. All study cohorts were randomised in a 2:1 ratio. Treatment duration for each cohort was 7 to 10 days. Patients were not permitted to switch to oral therapy.

Cohort 1: 15 patients treated with cefepime 1 g/AAI101 500 mg intravenous (i.v.) infusion over 2 hours once every 8 hours (q8h), and 7 patients treated with cefepime 1 g i.v. infusion over 2 hours q8h.

Cohort 2: 15 patients treated with cefepime 2 g/AAI101 750 mg i.v. infusion over 2 hours q8h, and 8 patients treated with cefepime 2 g i.v. infusion over 2 hours q8h.

Study Design

Conditions

Urinary Tract Infections

Intervention

Cefepime 1G - 2G / AAI101 0.5G - 0.75G, cefepime 1 g or cefepime 2 g

Location

Kromerizska nemocnice
Kromeriz
Czechia
76701

Status

Completed

Source

Allecra

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-09-27T07:04:18-0400

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Medical and Biotech [MESH] Definitions

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