Optimizing Metabolic Control in Type 1 Diabetes - The Automatic Bolus Calculator Flash Study

2018-09-28 06:43:12 | BioPortfolio


This study aims to compare the effect of flash glucose monitoring (FGM) with traditional self-monitoring of blood glucose (SMBG) with or without carbohydrate counting and automated bolus calculation, in patients with type 1 diabetes and poor metabolic control.

The investigators will include in total 200 patients recruited from 5 clinical sites in the Capital Region of Copenhagen.

The patients will be randomized into four groups; A) Standard diabetes training, i.e. group training in in general diabetes health issues, B) Group training in carbohydrate counting and automated bolus calculation, the app MySugr will be taught and downloaded, C) Group training as in group A, and instructed to use FGM, D) Group training as in group B, and besides training in the use of the app MySugr, also instructed to use FGM.

All patients are followed for 26 weeks with 6 clinical visits, group training (1 visit) and 2 telephone consultations.

The primary outcome is time spent in normoglycemia.

Study Design


Diabetes Mellitus, Type 1


Carbohydrate counting, automated bolus calculation, Flash glucose monitoring (FGM)


Steno Diabetes Center Copenhagen




Steno Diabetes Center

Results (where available)

View Results


Published on BioPortfolio: 2018-09-28T06:43:12-0400

Clinical Trials [2610 Associated Clinical Trials listed on BioPortfolio]

Efficacy of Automated Bolus Calculation in Type 2 Diabetes

The investigators hypothesize that non-optimal basal-bolus insulin treated patients with type 2 diabetes can achieve better metabolic control by counting carbohydrates with concurrent use ...

The Dietary Education Trial in Carbohydrate Counting (DIET-CARB Study): A Study Comparing Different Approaches to Dietary Self-management in Patients With Type 1 Diabetes

The study is designed to evaluate two different dietitian-led self-management approaches in carbohydrate counting compared to routine dietary care (control) on glycaemic control in adult p...

Does Protein and Fat Content of Meal Increase Glucose Concentrations

The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients wi...

An Evaluation of the FreeStyle Flash Glucose Monitoring System

The usability, skin reactions and accuracy of the FreeStyle Libre glucose monitoring system in children will be evaluated by questionnaires, pictures of the insertion site and comparison o...

An Evaluation of the FreeStyle Libre Flash Glucose Monitoring System

Medium-term (6-12 months) evaluation of the use, the identified problems, the usability and the effect on the metabolic control of the FreeStyle Flash Libre glucose monitoring system in 90...

PubMed Articles [9211 Associated PubMed Articles listed on BioPortfolio]

Disagreement between capillary blood glucose and flash glucose monitoring sensor can lead to inadequate treatment adjustments during pregnancy.

Continuous glucose monitoring tends to replace capillary blood glucose (CBG) self-monitoring. Our aim was to determine the agreement between CBG and a flash glucose monitoring system (Flash-GMS) in tr...

Improved well-being and decreased disease burden after 1-year use of flash glucose monitoring (FLARE-NL4).

The FreeStyle Libre is a flash glucose monitoring (FSL-FGM) system. Compared with finger-prick based self-monitoring of blood glucose, FSL-FGM may provide benefits in terms of improved glycemic contro...

Reduction in HbA1c using professional flash glucose monitoring in insulin-treated type 2 diabetes patients managed in primary and secondary care settings: A pilot, multicentre, randomised controlled trial.

Analyse the effects of professional flash glucose monitoring system (FreeStyle Libre Pro™) on glycaemic control in insulin-treated type 2 diabetes.

Freestyle libre flash glucose monitoring improves patient quality of life measures in children with Type 1 diabetes mellitus (T1DM) with appropriate provision of education and support by healthcare professionals.

In 2017 the UK's Association of Children's Diabetes Clinicians (ACDC) launched a national educational package to provide training in the use of Freestyle Flash glucose monitoring (GM) to healthcare pr...

Carbohydrate counting accuracy in adults with cystic fibrosis related diabetes.

Poorly controlled Cystic Fibrosis-Related Diabetes (CFRD) is associated with adverse impacts on lung function and nutritional status. Insulin therapy is the only recommended medical treatment. Carbohy...

Medical and Biotech [MESH] Definitions

Detection and counting of scintillations produced in a fluorescent material by ionizing radiation.

Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.

Self evaluation of whole blood glucose levels outside the clinical laboratory. A digital or battery-operated reflectance meter may be used. It has wide application in controlling unstable insulin-dependent diabetes.

Biosynthesis of GLUCOSE from nonhexose or non-carbohydrate precursors, such as LACTATE; PYRUVATE; ALANINE; and GLYCEROL.

Maintenance of a constant blood glucose level by perfusion or infusion with glucose or insulin. It is used for the study of metabolic rates (e.g., in glucose, lipid, amino acid metabolism) at constant glucose concentration.

More From BioPortfolio on "Optimizing Metabolic Control in Type 1 Diabetes - The Automatic Bolus Calculator Flash Study"

Quick Search

Searches Linking to this Trial