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Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients

2018-11-01 15:25:19 | BioPortfolio

Summary

Persistent cough is a distressing symptom for people with respiratory disorders. Patients also often experience an ongoing urge-to-cough that prompts coughing, and which fails to resolve the sensation. Understanding how the brain controls cough and the urge-to-cough could lead to new cough suppressing therapies. The overall objective of this project is to use functional brain imaging (fMRI) to identify brain regions that are involved in the exaggerated urge-to-cough in humans with chronic cough. Our focus will be on the brainstem where information from the airways first arrives in the central nervous system.

Study Design

Conditions

Cough

Intervention

Adenosine Triphosphate, Capsaicin, Functional Brain Imaging

Status

Not yet recruiting

Source

University of Melbourne

Results (where available)

View Results

Links

Published on BioPortfolio: 2018-11-01T15:25:19-0400

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Medical and Biotech [MESH] Definitions

An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.

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