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A Phase I Safety and Tolerability Study of PP-001 Eye Drops in Healthy Adult Volunteers

2018-12-14 02:26:19 | BioPortfolio

Published on BioPortfolio: 2018-12-14T02:26:19-0500

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This is a randomized, double-masked, vehicle-controlled study of the safety and efficacy of OTX-101 (0.09% cyclosporine nanomicellar solution) in the treatment of keratoconjunctivitis sicc...

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To report an outbreak of microsporidial keratoconjunctivitis resulting from a swimming pool in Taiwan.

Increased Lacrimal Fluid Level of HMGB1 in Vernal Keratoconjunctivitis.

The aim of the present prospective study was to evaluate the lacrimal fluid concentration of HMGB1 in young patients affected by Vernal Keratoconjunctivitis (VKC) compared to a control group of health...

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We found upregulation of 47 immunoglobulin genes and 22 S. aureus infection-related genes in refractory atopic keratoconjunctivitis tissue by RNA-seq analysis, suggesting that lymphoid neogenesis and ...

Immunopathological Features of Severe Chronic Atopic Keratoconjunctivitis and Effects of Topical Cyclosporine Treatment.

To assess differential roles of inflammatory cells in pathophysiology of severe atopic keratoconjunctivitis (AKC) and evaluate immunomodulatory effects of topical cyclosporine A (CsA).

Investigation of the efficacy of alcohol-based solutions on adenovirus serotypes 8, 19 and 37, the common cause of epidemic keratoconjunctivitis, after an adenovirus outbreak occurred in the hospital.

Hand antiseptics are of great importance in the prevention of nosocomial infections. Due to the frequent occurrence of adenoviral epidemic keratoconjunctivitis outbreaks in our hospital, we needed to ...

Medical and Biotech [MESH] Definitions

A species of gram-negative, aerobic bacteria that is most frequently isolated from bovine eyes in cases of infectious keratoconjunctivitis (KERATOCONJUNCTIVITIS, INFECTIOUS), but also occurs in unaffected eyes and the nasal cavity of cattle.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

Simultaneous inflammation of the cornea and conjunctiva.

A species of gram-negative bacteria causing CONJUNCTIVITIS and KERATOCONJUNCTIVITIS in SHEEP and GOATS.

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