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CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients

2018-12-14 02:26:19 | BioPortfolio

Published on BioPortfolio: 2018-12-14T02:26:19-0500

Clinical Trials [2423 Associated Clinical Trials listed on BioPortfolio]

AGe-adapted Benefits of Envarsus Versus Twice-daily Tacrolimus ImmunosuppressioN druGs After Kidney Transplantation

The proportion of elderly patients with end-stage kidney disease undergoing renal replacement therapy (RRT) is steadily increasing. Although kidney transplantation remains the optimal RRT ...

Converting Elderly Kidney Transplant Recipients From Tacrolimus to Envarsus to Limit Neurological AE and Improve QOL

This study will investigate whether converting patients from FDA approved immediate-release tacrolimus to FDA approved extended release tacrolimus (Envarsus) reduces neurological side-effe...

Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study

It is a prospective, single-arm, open-label, multicentre study with the principal aim to estimate tacrolimus pharmacokinetic parameters in elderly de-novo kidney transplant recipients of E...

Simultaneous Pancreas-Kidney Transplantation With Campath Protocol

The purpose of this study is to determine and compare the efficacy of Campath-1H/Tacrolimus versus ATG/Tacrolimus/MMF therapy in conjunction with initial short-term steroids in Type 1-diab...

CNS Study of Patients Switching From Tacrolimus to Envarsus

Pilot study documenting the neurotoxic side effects including tremors in patients with stable graft who are receiving Tacrolimus following kidney transplantation. Standardized questionnair...

PubMed Articles [5166 Associated PubMed Articles listed on BioPortfolio]

Simultaneous Pancreas-Kidney Transplantation Versus Living Donor Kidney Transplantation Alone: an Outcome-Driven Choice?

The choice of optimum transplant in a patient with type 1 diabetes mellitus (T1DM) and chronic kidney disease stage V (CKD V) is not clear. The purpose of this review was to investigate this in more d...

Development and validation of a prognostic model for kidney function 1 year after combined pancreas and kidney transplantation using pre-transplant donor and recipient variables.

The widening gap between demand and supply of organs for transplantation provides extraordinary challenges for ethical donor organ allocation rules. The transplant community is forced to define favora...

The Survival Advantage of Pancreas after Kidney Transplantation.

Patient Survival following Pancreas After Kidney transplantation (PAK) has been reported to be inferior to patient survival following Simultaneous Pancreas and Kidney transplantation (SPK). This analy...

Defining kidney allograft benefit from successful pancreas transplant: separating fact from fiction.

To define the natural history of kidney allograft loss related to recurrent diabetes following transplant, and to understand the potential benefit of pancreas transplantation upon kidney allograft sur...

Graft dysfunction in simultaneous pancreas kidney transplantation (spk): results of concurrent kidney and pancreas allograft biopsies.

Simultaneous pancreas and kidney transplants offer significant therapeutic advantages but present a diagnostic approach dilemma in the diagnosis of rejection. Since both organs are from the same donor...

Medical and Biotech [MESH] Definitions

The transference of a pancreas from one human or animal to another.

The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

The transference of a kidney from one human or animal to another.

General dysfunction of an organ occurring immediately following its transplantation. The term most frequently refers to renal dysfunction following KIDNEY TRANSPLANTATION.

Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.

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