Safety and Performance of the Journey™ II UNI Unicompartmental Knee System

2018-12-13 02:49:11 | BioPortfolio


This clinical study will evaluate the early to midterm safety and performance of the JOURNEY™ II UNI UKS in patients with non-inflammatory degenerative joint disease of the knee requiring lateral or medial knee compartment replacement. Clinical, radiographic, health economic and safety outcomes will be evaluated.


To assess the safety and performance of the JOURNEY™ II UNI UKS in patients with unicompartmental degeneration of the knee by demonstrating non-inferiority of the cumulative percent implant survival in subjects with the JOURNEY™ II UNI UKS implanted, compared to a literature reference rate of 91.7% (AOA annual report 2015)12 at 5 years.

Study Design


Non-inflammatory Degenerative Joint Disease (NIDJD) of the Knee


Journey™ II UNI Unicompartmental Knee System


Midwest Ortho at Rush
United States




Smith & Nephew, Inc.

Results (where available)

View Results


Published on BioPortfolio: 2018-12-13T02:49:11-0500

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Medical and Biotech [MESH] Definitions

Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

An instrument used to assess the results of rehabilitation from knee injuries, especially those requiring ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION. It measures recovery of knee joint function based on ACTIVITIES OF DAILY LIVING.

A region of the lower extremity immediately surrounding and including the KNEE JOINT.

Replacement for a knee joint.

Injuries to the knee or the knee joint.

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