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Expanded Access to Cefiderocol for the Intravenous Treatment of Severe Gram Negative Bacterial Infections

2018-12-26 06:27:10 | BioPortfolio

Published on BioPortfolio: 2018-12-26T06:27:10-0500

Clinical Trials [784 Associated Clinical Trials listed on BioPortfolio]

Procalcitonin Level and Kinetics in Children With Bacterial Infections

The purposes of this study are: 1. To determine whether procalcitonin level at admission of pediatric patients with bacterial infections can be used as a marker for prediction of d...

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

This study compares 2 different treatments administered to try to prevent serious bacterial infections (such as pneumonia) in HIV-positive children. A combination of drugs (azithromycin pl...

OR PathTrac (Tracking Intra-operative Bacterial Transmission)

Healthcare-associated infections occur frequently and are associated with patient harm. These infections are becoming more difficult to treat due to antibiotic resistance. It is important ...

biomArkers to differeNtiate bacTerial From vIral iNfEctions

ANTOINE is a prospective trial which aims to assess diagnostic performance of 7 biomarkers for the diagnosis of severe bacterial infections (SBI) in children aged from 7 days to 36 months....

Study Of Dalbavancin Drug Levels Achieved In Hospitalized Adolescents Who Are Receiving Antibiotic Therapy For Bacterial Infections

Adolescent subjects hospitalized for the treatment of bacterial infections will be given 1 gram of dalbavancin through their veins and levels of dalbavancin in blood and urine will be meas...

PubMed Articles [6347 Associated PubMed Articles listed on BioPortfolio]

Stability and low induction propensity of cefiderocol against chromosomal AmpC β-lactamases of Pseudomonas aeruginosa and Enterobacter cloacae.

The siderophore cephalosporin cefiderocol possesses in vitro activity against MDR Gram-negative bacteria. The stability of cefiderocol against serine- and metallo-type carbapenemases has been reported...

Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide.

Bacterial infections are common and life-threatening in patients with cirrhosis. Little is known about the epidemiology of bacterial infections in different regions. We performed a multicenter prospec...

In vitro activity of cefiderocol, a siderophore cephalosporin, against a recent collection of clinically relevant carbapenem-nonsusceptible Gram-negative bacilli, including serine carbapenemase- and metallo-β-lactamase-producing isolates (SIDERO-WT-2014 Study).

Cefiderocol is a siderophore cephalosporin in development for treatment of infections caused by Gram-negative bacilli including carbapenem-resistant and multidrug-resistant isolates. The β-lactamase ...

Identifying patients with bacterial infections using a combination of C-reactive protein, procalcitonin, TRAIL and IP-10 in the emergency department: a prospective observational cohort study.

To effectively reduce the unnecessary use of broad spectrum antibiotics in the emergency department(ED), patients with bacterial infections need to be identified accurately. We investigated the diagno...

Invasive Bacterial Infections in Infants Younger Than 60 Days With Skin and Soft Tissue Infections.

The objective of this study was to describe the frequency of invasive bacterial infections (IBIs) in young infants with skin and soft tissue infections (SSTIs) and the impact of IBI evaluation on disp...

Medical and Biotech [MESH] Definitions

Bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.

Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.

Inflammation of the lung parenchyma that is caused by bacterial infections.

Infections by bacteria, general or unspecified.

Infections caused by bacteria and fungi, general, specified, or unspecified.

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