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The Effect of Lipid Emulsions on Free Fatty Acids and Free Bilirubin in Premature Newborns

2019-03-06 03:17:21 | BioPortfolio

Summary

The goal of this research study is to compare the levels of free fatty acids and free bilirubin between two intravenous lipid emulsion products in premature newborns.

Study Design

Conditions

Prematurity

Intervention

Intralipid, 20% Intravenous Emulsion, SMOF lipid

Location

University Texas Houston HSC
Houston
Texas
United States
77030

Status

Not yet recruiting

Source

The University of Texas Health Science Center, Houston

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-03-06T03:17:21-0500

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A family of vertebrate and insect lipid droplet associated proteins. They consist of a conserved N-terminal PAT domain (an alpha-helical region of about 110 amino acids), an 11-mer repeat region, and lipid-binding hydrophobic regions or 4-helix bundles near their C-termini. Perilipins transiently or constitutively localize to LIPID DROPLETS in ADIPOCYTES and FOAM CELLS, especially in regions adjacent to the PLASMA MEMBRANE and ENDOPLASMIC RECTICULUM. They are critical for lipid droplet synthesis and homeostasis as well as the regulation of lipid metabolism. Genetic variations in perilipins are associated with ATHEROSCLEROSIS; OBESITY; and DIABETES MELLITUS.

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